This example shows PK parameters calculated from time-concentration profiles for the nicotine for one subject at Day 1. Note that PPRFTDTC is populated in order to link the PP records to the respective PC records.
Rows 1-2
Show parameters TMAX and CMAX for day 1.
Rows 13-24:
Show parameters AUC for Day 1. Note AUCALL was calculated as AUC from 0- to the last value and AUCINT was calculated as 0 to10 minutes. This interval is represented in PPSTINI, and PPENINT.
Row Captions Debug Message
Please construct row caption labels as instructed in <ac:link><ri:page ri:content-title="Constructing labels for row captions" ri:space-key="TTD"/></ac:link>.
pp.xpt
pp.xpt
Row
STUDYID
DOMAIN
USUBJID
PPSEQ
PPGRPID
PPTESTCD
PPTEST
PPCAT
PPORRES
PPORRESU
PPSTRESC
PPSTRESN
PPSTRESU
PPSPEC
PPANMETH
VISITNUM
VISIT
PPDTC
PPRFTDTC
PPSTINT
PPENINT
1
ABC-123
PP
123-0001
1
DAY1_PAR
TMAX
Time of CMAX
NICOTINE PARENT
5
m
5
5
m
PLASMA
non-compartmental analysis. and corrected for baseline
1
DAY 1
2002-01-07
2001-02-01T08:00
2
ABC-123
PP
123-0001
2
DAY1_PAR
CMAX
Max Conc
NICOTINE PARENT
13
ng/mL
13
13
ng/mL
PLASMA
non-compartmental analysis. and corrected for baseline
1
DAY 1
2002-01-07
2001-02-01T08:00
3
ABC-123
PP
123-0001
3
DAY1_PAR
AUCALL
AUC All
NICOTINE PARENT
11.4
h*ng/mL
11.4
11.4
h*ng/mL
PLASMA
non-compartmental analysis. and corrected for baseline
1
DAY 1
2002-01-07
2001-02-01T08:00
3
ABC-123
PP
123-0001
4
DAY1_PAR
AUCINT
AUC from T1 to T2
NICOTINE PARENT
6.0
h*ng/mL
6.0
6.0
h*ng/mL
PLASMA
non-compartmental analysis. and corrected for baseline