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Earlier last week, my colleague , in which he proposed the idea of "embedded keys" at 01:45 How would James, the fictitious forms designer, do to build a data capture form with these embedded keys?

Let's use the same vital signs example. First, we have a few widgets for the physical layer, i.e., variables. Together they form a wireframe of a vital signs data collection module. Each variable has a NCI c-code, a name, and a definition:

Swivel Chair - Variables

Next, we have several widgets for the medical concepts surrounding blood pressure. Similar to the variable widgets, they also have a NCI c-code, a name and a definition.:

Swivel Chair - Concepts

In the above diagram, motice how the c-code for Blood Pressure and Vital Signs begins with CUI, or Concept Unique Identifier. The fact is, in the NCI Metathesaurus, these concepts come pre-assembled with relationships, such that:

Swivel Chair - Concept relationship

The last set of widgets are the controlled terminology.

Swivel Chair - Codelists and codes

We have all the widgets, allowing us to assemble a well-defined capture form with all necessary "embedded keys".

Swivel Chair - Wireframe assembly

In conclusion, the "embedded keys" will not only serve as the conduit to the healthcare link side of interoperability, they can also be used to tie conceptual ideas (knowledge) to the physical implementations (SDTM). This way, it doesn't really matter the verbiages used on a CRF because the c-codes uphold the underlying sementics.

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