This example shows findings from an assessment of the unique pattern of allelic variation in genes of human leukocyte antigens (HLA), for purposes such as selecting cell, tissue and organ donors, diagnosing autoimmune diseases, determining the risk of adverse drug reactions, or to guide immunotherapies. An arbitrary identifier for the allele is represented in GFCOPYID. Patterns of HLA allele sequences are reported as short codes from a publicly available reference database.
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Rows 1-9, 11, 15-16: Show the characterization of the unique pattern of sequence variation for the allele of the HLA gene of interest represented in GFSYM. Rows 10, 12-14: Show attempted assessments for which results could not be generated due to sequence overlap with the detected DRB1 allele.
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Row STUDYID DOMAIN USUBJID GFSEQ GFREFID GFTESTCD GFTEST GFTSTDTL GFORRES GFSYM GFSYMTYP GFCOPYID GFSTAT GFREASND GFNAM GFSPEC GFMETHOD VISITNUM VISIT VISITDY GFDTC GFDY 1 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE A*02:TSXZ HLA-A GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 2 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE A*03:ABSAX HLA-A GENE WITH PROTEIN PRODUCT 2 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 3 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE B*18:TXYF HLA-B GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 4 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE B*38:01 HLA-B GENE WITH PROTEIN PRODUCT 2 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 5 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE C*07:AAEPN HLA-C GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 6 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE C*12:AAGWE HLA-C GENE WITH PROTEIN PRODUCT 2 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 6 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DRB1*07:ACEUA HLA-DRB1 GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 7 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DRB1*14:ABZZV HLA-DRB1 GENE WITH PROTEIN PRODUCT 2 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 9 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DRB3*01:XX HLA-DRB3 GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 10 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE HLA-DRB3 GENE WITH PROTEIN PRODUCT 2 NOT DONE DRB3* ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 11 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DRB4*01:FVUU HLA-DRB4 GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 12 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE HLA-DRB4 GENE WITH PROTEIN PRODUCT 2 NOT DONE DRB4* ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 13 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE HLA-DRB5 GENE WITH PROTEIN PRODUCT 1 NOT DONE DRB5* ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 14 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE HLA-DRB5 GENE WITH PROTEIN PRODUCT 2 NOT DONE DRB5* ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 15 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DQB1*02:ACBXN HLA-DQB1 GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 16 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DQB1*05:ACEDB HLA-DQB1 GENE WITH PROTEIN PRODUCT 2 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2
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