Tobacco product HPHC testing results are represented in the PT domain. This example shows HPHC testing with an ENDS device. HPHC testing is conducted on samples of the product of interest, and (if applicable) samples of comparison products. Each product tested would have its own unique applicant-defined value for SPTOBID to identify the product.
| Row 1: | Shows the HPHC testing performed for acetaldehyde from a sample of e-Liquid (as indicated by PTSPEC=E-LIQUID). | | Rows 2-4: | Show the HPHC testing performed for 3 analytes from aerosol produced using the non-intense regimen on a smoking machine. PTSPEC=AEROSOL, SPDEVID indicates the smoking machine used to produce the aerosol, and PTREFID indicates the vaping regimen. | | Rows 5-7: | Show the HPHC testing performed for 3 analytes using the intense regimen on the same smoking machine (PTREFID=INTENSE REGIMEN). |
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| Row | STUDYID | DOMAIN | SPTOBID | SPDEVID | PTSEQ | PTREFID | PTTESTCD | PTTEST | PTCAT | PTSCAT | PTORRES | PTORRESU | PTSTRESC | PTSTRESN | PTSTRESU | PTSPEC | PTREPNUM | PTDTC |
|---|
| 1 | TOB08 | PT | ENDS02a |
| 1 |
| ACTALD | Acetaldehyde | HPHC TESTING | HPHC | 7.9 | µg/mL | 7.9 | 7.9 | µg/mL | E-LIQUID | 1 | 2022-09-30 | | 2 | TOB08 | PT | ENDS02a | PUFFMASTER3K | 2 | NON-INTENSE REGIMEN | NICOTINE | Nicotine | HPHC TESTING | HPHC | 53.5 | µg/puff | 53.5 | 53.5 | µg/puff | AEROSOL | 1 | 2022-09-30 | | 3 | TOB08 | PT | ENDS02a | PUFFMASTER3K | 3 | NON-INTENSE REGIMEN | ACTALD | Acetaldehyde | HPHC TESTING | HPHC | 34.7 | ng/puff | 34.7 | 34.7 | ng/puff | AEROSOL | 1 | 2022-09-30 | | 4 | TOB08 | PT | ENDS02a | PUFFMASTER3K | 4 | NON-INTENSE REGIMEN | BNZOICAC | Benzoic Acid | HPHC TESTING | Other | 43.3 | µg/puff | 43.3 | 43.3 | µg/puff | AEROSOL | 1 | 2022-09-30 | | 5 | TOB08 | PT | ENDS02a | PUFFMASTER3K | 5 | INTENSE REGIMEN | NICOTINE | Nicotine | HPHC TESTING | HPHC | 105 | µg/puff | 105 | 105 | µg/puff | AEROSOL | 2 | 2022-09-30 | | 6 | TOB08 | PT | ENDS02a | PUFFMASTER3K | 6 | INTENSE REGIMEN | ACTALD | Acetaldehyde | HPHC TESTING | HPHC | 43.5 | ng/puff | 43.5 | 43.5 | ng/puff | AEROSOL | 2 | 2022-09-30 | | 7 | TOB08 | PT | ENDS02a | PUFFMASTER3K | 7 | INTENSE REGIMEN | BNZOICAC | Benzoic Acid | HPHC TESTING | Other | 84.1 | µg/puff | 84.1 | 84.1 | µg/puff | AEROSOL | 2 | 2022-09-30 |
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The identifying characteristics of the smoking machine are represented in the DI reference dataset.
| Row | STUDYID | DOMAIN | SPDEVID | DISEQ | DIPARMCD | DIPARM | DIVAL |
|---|
| 1 | TOB07 | DI | PUFFMASTER3K | 1 | DEVTYPE | Device Type | Smoking Machine |
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| 2 | TOB07 | DI | PUFFMASTER3K | 2 | MANUF | Manufacturer | Acme |
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| 3 | TOB07 | DI | PUFFMASTER3K | 3 | TRADENAM | Trade Name | PuffMaster 3000 |
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Details of the vaping regimen performed by the smoking machine are represented as device in-use properties, linked to the HPHC testing results in PT by matching values of PTREFID/DUREFID.
| Rows 1-9: | Show the parameters of the non-intense vaping regimen. | | Rows 8-9: | Note the use of DUGRPID to group these records together to indicate that puff pause and puff pause interval are related records. Taken together, they indicate that this vaping regimen pauses for 60 seconds every 10 puffs. | | Rows 10-18: | Show the parameters of the intense vaping regimen. | | Rows 17-18: | Note the use of DUGRPID to group these records together to indicate that puff pause and puff pause interval are related records. Taken together, they indicate that this vaping regimen pauses for 30 seconds every 10 puffs. |
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| Row | STUDYID | DOMAIN | SPDEVID | DUSEQ | DUREFID | DUGRPID | DUTESTCD | DUTEST | DUORRES | DUORRESU | DUSTRESC | DUSTRESN | DUSTRESU |
|---|
| 1 | TOB07 | DU | PUFFMASTER3K | 1 | NON-INTENSE REGIMEN |
| PUFFPROF | Puff Profile | SQUARE |
| SQUARE |
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| | 2 | TOB07 | DU | PUFFMASTER3K | 2 | NON-INTENSE REGIMEN |
| PUFFDUR | Puff Duration | 1.25 | sec | 1.25 | 1.25 | sec | | 3 | TOB07 | DU | PUFFMASTER3K | 3 | NON-INTENSE REGIMEN |
| PUFFINT | Puff Interval | 7 | PUFF/min | 7 | 7 | PUFF/min | | 4 | TOB07 | DU | PUFFMASTER3K | 4 | NON-INTENSE REGIMEN |
| PUFFBLCK | Puff Block | 25 | % | 25 | 25 | % | | 5 | TOB07 | DU | PUFFMASTER3K | 5 | NON-INTENSE REGIMEN |
| | Number of Puffs | 200 | PUFF | 200 | 200 | PUFF | | 6 | TOB07 | DU | PUFFMASTER3K | 6 | NON-INTENSE REGIMEN |
| PUFFVOL | Puff Volume | 10 | mL | 10 | 10 | mL | | 7 | TOB07 | DU | PUFFMASTER3K | 7 | NON-INTENSE REGIMEN |
| PUFFRNG | Puff Range | 100-200 |
| 100-200 |
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| | 8 | TOB07 | DU | PUFFMASTER3K | 8 | NON-INTENSE REGIMEN | 1 | PUFFPAUS | Puff Pause | 60 | s | 60 | 60 | s | | 9 | TOB07 | DU | PUFFMASTER3K | 9 | NON-INTENSE REGIMEN | 1 | PUFFPINT | Puff Pause Interval | 10 | PUFF | 10 | 10 | PUFF | | 10 | TOB07 | DU | PUFFMASTER3K | 1 | INTENSE REGIMEN |
| PUFFPROF | Puff Profile | SQUARE |
| SQUARE |
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| | 11 | TOB07 | DU | PUFFMASTER3K | 2 | INTENSE REGIMEN |
| PUFFDUR | Puff Duration | 3.25 | sec | 3.25 | 3.25 | sec | | 12 | TOB07 | DU | PUFFMASTER3K | 3 | INTENSE REGIMEN |
| PUFFINT | Puff Interval | 10 | PUFF/min | 10 | 10 | PUFF/min | | 13 | TOB07 | DU | PUFFMASTER3K | 4 | INTENSE REGIMEN |
| PUFFBLCK | Puff Block | 25 | % | 25 | 25 | % | | 14 | TOB07 | DU | PUFFMASTER3K | 5 | INTENSE REGIMEN |
| PUFFNUM | Number of Puffs | 300 | PUFF | 300 | 300 | PUFF | | 15 | TOB07 | DU | PUFFMASTER3K | 6 | INTENSE REGIMEN |
| PUFFVOL | Puff Volume | 25 | mL | 25 | 25 | mL | | 16 | TOB07 | DU | PUFFMASTER3K | 7 | INTENSE REGIMEN |
| PUFFRNG | Puff Range | 100-400 |
| 100-400 |
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| | 17 | TOB07 | DU | PUFFMASTER3K | 8 | INTENSE REGIMEN | 2 | PUFFPAUS | Puff Pause | 10 | s | 10 | 10 | s | | 18 | TOB07 | DU | PUFFMASTER3K | 9 | INTENSE REGIMEN | 2 | PUFFPINT | Puff Pause Interval | 30 | PUFF | 30 | 30 | PUFF |
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