Smoking/vaping puff topography is how a smoker smokes or vapes a tobacco product. Measures of vaping/smoking behavior is critical to understanding exposure to biomarkers of nicotine and toxins. Topography devices are used to measure cigarette and e-cigarette puffing behavior. Puff inhalation and exhalation duration, puff volume, and inter-puff interval are often measured. 

Puff topography is typically considered data about the subject's exposure to the test product. As these data represent information about study product exposure, the data is represented in the Exposure (EX) domain (see Section 3.3.4, Exposure Assessments During Tobacco Product Studies).

Puff topography is often measured using smoking machines. Information about devices—not the study subject nor the study itself—are represented using the SDTM Device domains. 

Reference:

CORESTA. Assessing Product Use Behaviour and Exposure: Definitions and Methods. October 2022. Accessed October 17, 2023. https://www.coresta.org/assessing-product-use-behaviour-and-exposure-definitions-and-methods-36737.html