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Description of the context of the example for colleagues:
This example shows findings from an assessment of the unique pattern of allelic variation in genes of human leukocyte antigens (HLA), for purposes such as selecting cell, tissue and organ donors, diagnosing autoimmune diseases, determining the risk of adverse drug reactions, or to guide immunotherapies.
HLA Nomenclature @ hla.alleles.org
gf.xpt
Rows 1-6, 9-14: Rows 10, 12-14:
gf.xpt
gf.xpt
Row # STUDYID DOMAIN USUBJID SPDEVID NHOID GFSEQ GFGRPID GFREFID GFSPID GFLNKID GFLNKGRP GFTESTCD GFTEST GFTSTDTL GFORRES GFSYM GFSYMTYP GFCOPYID GFSTAT GFREASND GFXFN GFNAM GFSPEC GFMETHOD GFRUNID GFANMETH GFBLFL GFDRVFL GFLLOQ GFREPNUM VISITNUM VISIT VISITDY GFDTC GFDY GFTPT GFTPTNUM GFELTM GFTPTREF GFRFTDTC 1 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE A*02:TSXZ HLA-A GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING -1 SCREENING -1 9/16/2023 -2 2 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE A*03:ABSAX HLA-A GENE WITH PROTEIN PRODUCT 2 ACME Genomics DNA SANGER SEQUENCING 3 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE B*18:TXYF HLA-B GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING 4 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE B*38:01 HLA-B GENE WITH PROTEIN PRODUCT 2 ACME Genomics DNA SANGER SEQUENCING 5 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE C*07:AAEPN HLA-C GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING 6 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE C*12:AAGWE HLA-C GENE WITH PROTEIN PRODUCT 2 ACME Genomics DNA SANGER SEQUENCING 6 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DRB1*07:ACEUA HLA-DRB1 GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING 7 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DRB1*14:ABZZV HLA-DRB1 GENE WITH PROTEIN PRODUCT 2 ACME Genomics DNA SANGER SEQUENCING 9 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DRB3*01:XX HLA-DRB3 GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING 10 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE HLA-DRB3 GENE WITH PROTEIN PRODUCT 2 NOT DONE DRB3* ACME Genomics DNA SANGER SEQUENCING 11 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DRB4*01:FVUU HLA-DRB4 GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING 12 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE HLA-DRB4 GENE WITH PROTEIN PRODUCT 2 NOT DONE DRB4* ACME Genomics DNA SANGER SEQUENCING 13 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE HLA-DRB5 GENE WITH PROTEIN PRODUCT 1 NOT DONE DRB5* ACME Genomics DNA SANGER SEQUENCING 14 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE HLA-DRB5 GENE WITH PROTEIN PRODUCT 2 NOT DONE DRB5* ACME Genomics DNA SANGER SEQUENCING 15 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DQB1*02:ACBXN HLA-DQB1 GENE WITH PROTEIN PRODUCT 1 ACME Genomics DNA SANGER SEQUENCING 16 Study-123 GF S123-001 1 HGA4567 VARPROF Variant Profile ALLELE TYPE DQB1*05:ACEDB HLA-DQB1 GENE WITH PROTEIN PRODUCT 2 ACME Genomics DNA SANGER SEQUENCING
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