Representation of the various aortic anyrusms

There are many types of Aortic Aneurysms, the two major types are:

TAA: thoracic aortic aneurysm, may further be sub-classified based on location:
1. Ascending aortic aneurysm
2. Aortic arch aneurysm
3. Descending aortic aneurysm
4. Aneurysm that straddles multiple portions of the aorta (i.e. from aortic arch to descending aorta)

AAA: abdominal aortic aneurysm, may further be:
1. Above the renal artery
2. Below the renal artery
3. In the renal artery

You don’t know if someone has aortic aneurysms. You may do screening tests based on family history. Sometimes, some symptoms may be experienced such as back pain, chest pain, pain in the lower abdomen that may be indicative of aortic aneurysm. If someone does have TAA, the possibility of synchronous and metachronous TAAs may be present. So you look at both chest and abdomen. If AAA is present but TAA is not, you make a note too.

Case 1 - Subject has both TAA and AAA

The subject had CT scans performed at the chest and abdomen to look for the presence of aneurysms, if there are any:

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pr.xpt

Row	STUDYID	DOMAIN	USUBJID	PRSEQ	PRTRT	PRLOC	VISIT
1	ABC	PR	ABC-123	1	CT SCAN	CHEST	BASELINE
2	ABC	PR	ABC-123	2	CT SCAN	ABDOMEN	BASELINE

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If both AAA and TAA are found, and modeled as CE:

Note: in this case CE works because both TAA and AAA are detected so you would have separate CE record for each "identified" aneurysm.

ce.xpt

Row	STUDYID	DOMAIN	USUBJID	CESEQ	CETRT	CELOC	VISIT	CE LOC Detail
1	ABC	CE	ABC-123	1	aneurysm	thoracic cavity	BASELINE	aortic root
2	ABC	CE	ABC-123	2	aneurysm	thoracic cavity	BASELINE	Aortic arch to descending aorta
3	ABC	CE	ABC-123	3	aneurysm	abdominal cavity	BASELINE	Left renal artery
4	ABC	CE	ABC-123	4	aneurysm	abdominal cavity	BASELINE	Infrarenal artery (Below the kidneys)

Dataset Debug Message

There are eight leading, trailing, or non-breaking spaces in the dataset.

If both AAA and TAA are found, and modeled as CV:

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cv.xpt

Row	STUDYID	DOMAIN	USUBJID	CVSEQ	CVGRPID	CVTEST	CVORRES	CVORRESU	CVLOC	CVLAT	CVLOCDTL	CVMETHOD	VISITNUM	VISIT	CVDTC	CV RES LOC	CV RES LAT	CV Result LOC detail
1	ABC	CV	ABC-123	1	1	Aneurysm Indicator	Y		thoracic cavity			CT SCAN	1	BASELINE	2020-04-27	Aorta
2	ABC	CV	ABC-123	2	1	Number of Aneurysms	2		thoracic cavity			CT SCAN	1	BASELINE	2020-04-27	Aorta
3	ABC	CV	ABC-123	3	1	Aneurysm Length/Diameter	2	CM	aorta			CT SCAN	1	BASELINE	2020-04-27	Aortic root
					1	Dissection Indicator	N
3	ABC	CV	ABC-123	4	1	Aneurysm Length/Diameter	7.5	CM	aorta			CT SCAN	1	BASELINE	2020-04-27			Aortic Arch to Descending Aorta
					1	Dissection Indicator	Y		aorta									Aortic Arch to Descending Aorta
					1	Stanford AoD Classification	TYPE B		aorta									Aortic Arch to Descending Aorta
4	ABC	CV	ABC-456	1	2	Aneurysm Indicator	Y		abdominal cavity			CT SCAN	1	BASELINE	2020-04-27	RENAL ARTERY	LEFT
5	ABC	CV	ABC-456	2	2	Aneurysm Length/Diameter	3	CM	renal artery	left		CT SCAN	1	BASELINE	2020-04-27
6	ABC	CV	ABC-456	3	3	Aneurysm Indicator	Y		abdominal cavity			CT SCAN	1	BASELINE	2020-04-27			Infrarenal artery (Below the kidneys)
7	ABC	CV	ABC-456	4	3	Aneurysm Length/Diameter	2	CM	abdominal cavity		Infrarenal artery (Below the kidneys)	CT SCAN	1	BASELINE	2020-04-27

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Case 2 - Subject has AAA but TAA is not found

The subject had CT scans performed at the chest and abdomen to look for the presence of aneurysms, if there are any:

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pr.xpt

Row	STUDYID	DOMAIN	USUBJID	PRSEQ	PRTRT	PRLOC	VISIT
1	ABC	PR	ABC-456	1	CT SCAN	CHEST	BASELINE
2	ABC	PR	ABC-456	2	CT SCAN	ABDOMEN	BASELINE

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If AAA is found but TAA is not:

a CE record for AAA will be created;
a CE record for TAA will not be created - the fact that synchronous TAA is not detected, this information is lost. But a procedure of chest CT scan was performed, what came off of that procedure? we will never know.

ce.xpt

Row	STUDYID	DOMAIN	USUBJID	CESEQ	CETRT	CELOC	VISIT		CE LOC Detail
1	ABC	CE	ABC-456	1	aneurysm	abdominal cavity	BASELINE		Infrarenal artery (Below the kidneys)

Dataset Debug Message

There are two leading, trailing, or non-breaking spaces in the dataset.

If I were to model this in CV, I could show that AAA is detected along with its diameter measurement. On top of that, TAA is not detected.

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cv.xpt

Row	STUDYID	DOMAIN	USUBJID	CVSEQ	CVGRPID	CVTEST	CVORRES	CVORRESU	CVLOC	CVLOCDTL	CVMETHOD	VISITNUM	VISIT	CVDTC	CV Result LOC detail
1	ABC	CV	ABC-456	1	1	Aneurysm Indicator	Y		abdominal cavity		CT SCAN	1	BASELINE	2020-04-27	Infrarenal artery (Below the kidneys)
2	ABC	CV	ABC-456	2	1	Aneurysm Length/Diameter	2	CM	abdominal cavity	Infrarenal artery (Below the kidneys)	CT SCAN	1	BASELINE	2020-04-27
3	ABC	CV	ABC-456	1		Aneurysm Indicator	N		thoracic cavity		CT SCAN	1	BASELINE	2020-04-27

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Case 1 - Subject has both TAA and AAA

Case 2 - Subject has AAA but TAA is not found