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This example is currently in draft.

This example shows findings from an assessment of a genomic sequence rearrangement with the purpose of determining the characteristics of a fusion event between the BRD4 and MYO10 genes. The identifier for the genome reference used to generate the reported result is shown in GFGENREF. 

Glenn Barnes -

...

...

Dataset wrap
Namegf
Rowcaps
Row 1:

Shows the predicted functional impact

on expression

of the BRD4 and MYO10

genes caused by the genomic

sequence rearrangement.

Row 2:

Shows the first gene, BRD4, involved in the fusion event. The designation (name or number) of the chromosome

or contig

on which the variant appears is shown in GFCHROM. The published symbol for the gene of interest is shown in GFSYM. The description of the type of genomic entity that is represented by the published symbol in GFSYM is shown in GFSYMTYP as GENE WITH PROTEIN PRODUCT. The location within a sequence for the observed value in GFORRES is shown in GFGENLOC. 

Row 3:Shows the second gene, MYO10, involved in the fusion event. The designation (name or number) of the chromosome
or contig
on which the variant appears is shown in GFCHROM. The published symbol for the gene of interest is shown in GFSYM. The description of the type of genomic entity that is represented by the published symbol in GFSYM is shown in GFSYMTYP as GENE WITH PROTEIN PRODUCT. The location within a sequence for the observed value in GFORRES is shown in GFGENLOC. 
Row 4:

Shows

the description

the characterization or classification of the structural changes to the genes as a consequence of the

genomic rearrangement's impact on the coding

sequence rearrangement BRD4 and MYO10 genes.

Row 5:

Shows the

... .

predicted effect of the sequence rearrangement on the original reading frames of the BRD4 and MYO10 genes.

Row 6:Shows the read depth, the total number of times the locus of the fusion event was sequenced.
Dataset2
RowSTUDYIDDOMAINUSUBJIDGFSEQGFGRPIDGFREFIDGFTESTCDGFTESTGFTSTDTLGFORRESGFORRESUGFSTRESCGFSTRESNGFSTRESUGFGENREFGFCHROMGFSYMGFSYMTYPGFGENLOCGFXFNGFNAMGFSPECGFMETHODVISITNUMVISITVISITDYGFDTCGFDY
1GR123GF100001111TRF001338(TBD)SEQREARSequence Rearrangement"

REARRANGEMENT IMPACT

"

CLASSIFICATION

likely pathogenic
likely pathogenic

GRCh37.75



/compbio/analysis/120718_SN855_0084_AD13D5ACXX_LCNL-361/sampleAnalysis/sample18.TRF001338.01/TRF001338.01.vars.final.xmlACME XYZDNATARGETED GENOME SEQUENCING1SCREENING12022-01-252
2GR123GF100001221TRF001338(TBD)SEQREARSequence Rearrangement"REARRANGEMENT PARTNER GENE 1"BRD4
BRD4

GRCh37.7519BRD4GENE WITH PROTEIN PRODUCT15383893-15384049/compbio/analysis/120718_SN855_0084_AD13D5ACXX_LCNL-361/sampleAnalysis/sample18.TRF001338.01/TRF001338.01.vars.final.xmlACME XYZDNATARGETED GENOME SEQUENCING1SCREENING12022-01-252
3GR123GF100001331TRF001338(TBD)SEQREARSequence Rearrangement"REARRANGEMENT PARTNER GENE 2"MYO10
MYO10

GRCh37.755MYO10GENE WITH PROTEIN PRODUCT16724239-16724557/compbio/analysis/120718_SN855_0084_AD13D5ACXX_LCNL-361/sampleAnalysis/sample18.TRF001338.01/TRF001338.01.vars.final.xmlACME XYZDNATARGETED GENOME SEQUENCING1SCREENING12022-01-252
4GR123GF100001441TRF001338(TBD)SEQREARSequence Rearrangement"VARIANT DESCRIPTION"

REARRANGEMENT TYPE

truncation
truncation

GRCh37.75



/compbio/analysis/120718_SN855_0084_AD13D5ACXX_LCNL-361/sampleAnalysis/sample18.TRF001338.01/TRF001338.01.vars.final.xmlACME XYZDNATARGETED GENOME SEQUENCING1SCREENING12022-01-252
5GR123GF100001551TRF001338(TBD)SEQREARSequence Rearrangement"

PREDICTED IN-FRAME

"

INDICATOR

unknown
unknown

GRCh37.75



/compbio/analysis/120718_SN855_0084_AD13D5ACXX_LCNL-361/sampleAnalysis/sample18.TRF001338.01/TRF001338.01.vars.final.xmlACME XYZDNATARGETED GENOME SEQUENCING1SCREENING12022-01-252
6GR123GF100001661TRF001338(TBD)SEQREARSequence RearrangementREAD DEPTH45
4545
GRCh37.75



/compbio/analysis/120718_SN855_0084_AD13D5ACXX_LCNL-361/sampleAnalysis/sample18.TRF001338.01/TRF001338.01.vars.final.xmlACME XYZDNATARGETED GENOME SEQUENCING1SCREENING12022-01-252