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1. There are 3 components of tumor staging, frequently called TNM staging. These components are turmor tumor size (T), the extent of regional lymph nodes (N), and the extent of distant metastasis (M). Each component is classified with a combination of letters and numbers (e.g., "T0", "M1a"). For the AJCC V7, the classification results are stored in RSORRES and RSSTRESC.
   
   1. In addition to TNM staging, the absence or presence of residual tumor after treatment can be represented in RSTESTCD = AJCC105 with values stored in RSORRES and RSSTRESC (e.g., RSORRES and RSSTRESC = "RX").
2. TNM staging codes are typically assigned according to staging windows (e,g., clinical, pathological, recurrent, posttherapy, autopsy). These staging windows are identified using prefixes (e.g., c, p, a, yc, yp, r). Often the c prefix is assumed and not included. When prefixes are used, they are appended to the TNM staging codes (e.g., RSORRES = "rT1aN2M0"); the prefix r is appended to the TNM code and stored in RSORRES and RSSTRESC. See Section 4, SDTM Mapping Strategy, for further details.

3. For the AJCC V7 instrument, the type of cancer is stored in RSSCAT (e.g., For lung cancer, RSSCAT = "LUNG CANCER").

4. The text descriptions and definitions associated with each TNM code are specific to each cancer type. These text descriptions of the codes are not represented in the dataset.

5. Records are created in rs.xpt for every instrument item: 

   1. For items with no data, RSORRES, RSSTRESC, and RSSTRESN are all missing and QSSTAT = "NOT DONE". If the reason is known then that reason is represented in RSREASND (e.g., RSREASND = "PREFER NOT TO ANSWER"). If the reason is unknown, then RSSTAT = "NOT DONE" and RSREASND is missing.

6. Terminology:

   1. RSCAT, RSTESTCD, and RSTEST use approved CDISC Controlled Terminology.

   2. An example list of value sets for the result field is provided in Section 4, SDTM Mapping Strategy.  

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