https://www.sciencedirect.com/science/article/pii/S004060311930752X
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The following example illustrates the representation of an ENDS tobacco product's identifiers and descriptors using the TO domain. Note that this example makes use of TOCAT (Category of Tobacco Product ID Element, a permissible variable) uses TOSCAT to emphasize and differentiate the two 2 distinct types of parameters represented in TO: tobacco product identifiers and tobacco product descriptors.
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| Row | STUDYID | DOMAIN | SPTOBID | TOSEQ | TOPARMCD | TOPARM | TOCAT | TOSCAT | TOVAL | TOVALU |
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| 1 | TOB09 | TO | VAPE-Z27 | | TBPRDCAT | Tobacco Product Category | NEW PRODUCT | PRODUCT IDENTIFIER | Electronic Nicotine Delivery Systems (ENDS) ( |
VAPES| Vapes) |
| | 2 | TOB09 | TO | VAPE-Z27 | 2 | TBPRSCAT | Tobacco Product Subcategory | NEW PRODUCT | PRODUCT IDENTIFIER | Closed E-Cigarette |
| | 3 | TOB09 | TO | VAPE-Z27 | 3 | MANUF | Manufacturer | NEW PRODUCT | PRODUCT IDENTIFIER | Joes Vapes USA |
| | 4 | TOB09 | TO | VAPE-Z27 | 4 | TRADENAM | Trade Name | NEW PRODUCT | PRODUCT IDENTIFIER | Everyday Rich Tobacco |
| | 5 | TOB09 | TO | VAPE-Z27 | 5 | PACKTYP | Package Type | NEW PRODUCT | PRODUCT DESCRIPTOR | BOX |
| | 6 | TOB09 | TO | VAPE-Z27 | 6 | PRDQUAN | Product Quantity | NEW PRODUCT | PRODUCT DESCRIPTOR | 1 | E-CIGARETTE | | 7 | TOB09 | TO | VAPE-Z27 | 7 | LENGTH | Length | NEW PRODUCT | PRODUCT DESCRIPTOR | 107.2 | mm | | 8 | TOB09 | TO | VAPE-Z27 | 8 | DIAMETER | Diameter | NEW PRODUCT | PRODUCT DESCRIPTOR | 9 | mm | | 9 | TOB09 | TO | VAPE-Z27 | 9 | NICTNCNC | Nicotine Concentration | NEW PRODUCT | PRODUCT DESCRIPTOR | 2 | mg/L | | 10 | TOB09 | TO | VAPE-Z27 | 10 | PRPYLGLY | Propylene Glycol | NEW PRODUCT | PRODUCT DESCRIPTOR | 50 | % | | 11 | TOB09 | TO | VAPE-Z27 | 11 | VEGGLY | Vegetable Glycerin | NEW PRODUCT | PRODUCT DESCRIPTOR | 50 | % | | 12 | TOB09 | TO | VAPE-Z27 | 12 | CHARFLAV | Characterizing Flavor | NEW PRODUCT | PRODUCT DESCRIPTOR |
TOBACCO| Tobacco |
| | 13 | TOB09 | TO | VAPE-Z27 | 13 |
VOLUMEEVolume, liquidLiquid Volume | NEW PRODUCT | PRODUCT DESCRIPTOR | 1 | mL | | 14 | TOB09 | TO | VAPE-Z27 | 14 |
WATTWattage15 | TOB09 | TO | VAPE-Z27 | 15 | BATTCAPC | Battery Capacity | PRODUCT DESCRIPTOR | 5.2 | Watt | 1616DISPCRTG| DSCRTIND | Disposable Cartridge Indicator | NEW PRODUCT | PRODUCT DESCRIPTOR | Y |
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The manufacturing parameter specifications of the ENDS product as intended for used are represented in the Product Design Parameters ( PD ) domain. The following example below shows the target, minimum, and maximum values associated with each of 33 separate design parameters. These parameters are defined manufacturing specifications, not characteristics that are determined experimentally.
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| Row | STUDYID | DOMAIN | SPTOBID | PDSEQ | PDPARMCD | PDPARM | PDVALTRG | PDVALMIN | PDVALMAX | PDVALU |
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| 1 | TOB09 | PD | VAPE-Z27 | | DRWRST | Draw Resistance | 90.0 | 80.0 | 120.0 | mm H2O | | 2 | TOB09 | PD | VAPE-Z27 | 2 | PUFCNT | Puff Count | 300 | 290 | 310 |
| | 3 | TOB09 | PD | VAPE-Z27 | 3 | CRTVOL | Cartridge Volume | 3 | 1 | 5 | mL | | 4 | TOB09 | PD | VAPE-Z27 | 4 | HTELNUM | Number of Heating Elements | 1 | 1 | |
| | 5 | TOB09 | PD | VAPE-Z27 | 5 | HTELGTH | Heating Element Length | 3 | 2.7 | 3.3 | mm | | 6 | TOB09 | PD | VAPE-Z27 | 6 | HTEDIAM | Heating Element Diameter | 3 | 2.9 | 3.2 | mm | | 7 | TOB09 | PD | VAPE-Z27 | 7 | HTELRST | Heating Element Resistance | 0.75 | 0.25 | 1.5 | ohm | | 8 | TOB09 | PD | VAPE-Z27 | 8 | HTELRNG | Heating Element Range | 175 | 100 | 250 | C | | 9 | TOB09 | PD | VAPE-Z27 | 9 | HTELCFG | Heating Element Configuration | SPIRAL | SPIRAL | SPIRAL |
| | 10 | TOB09 | PD | VAPE-Z27 | 10 | BTVLTORG | Battery Voltage Operating Range | 4.5 | 3 | 6 | V | | 11 | TOB09 | PD | VAPE-Z27 | 11 | BTCRTORG | Battery Current Operating Range | 1000 | 650 | 1600 | mAh | | 12 | TOB09 | PD | VAPE-Z27 | 12 | BATCAPC | Battery Capacity | 1100 | 800 | 3000 | mAh | | 13 | TOB09 | PD | VAPE-Z27 | 13 | BATNOMV | Battery Nominal Voltage | 4.2 | 4.0 | 4.5 | V | | 14 | TOB09 | PD | VAPE-Z27 | 14 | BTCRTRT | Battery Current Rating | 2500 | 2000 | 2800 | mA | | 15 | TOB09 | PD | VAPE-Z27 | 15 | BTCHTPL | Battery Charging Temperature Limits | 200 | 100 | 315 | C | | 16 | TOB09 | PD | VAPE-Z27 | 16 | BTDCTMPL | Battery Discharge Temperature Limits | 20 | -20 | 60 | C | | 17 | TOB09 | PD | VAPE-Z27 | 17 | BTENDCV | Battery End of Discharge Voltage | 3.0 | 2.0 | 3.5 | V | | 18 | TOB09 | PD | VAPE-Z27 | 18 | BTMXCHC | Battery Maximum Charging Current | 24 | 20 | 30 | mA | | 19 | TOB09 | PD | VAPE-Z27 | 19 | BTMXDCC | Battery Maximum Discharging Current | 2700 | 2400 | 3000 | mA | | 20 | TOB09 | PD | VAPE-Z27 | 20 | BTULCHV | Battery Upper Limits Charging Voltage | 4.2 | 4.1 | 4.3 | V | | 21 | TOB09 | PD | VAPE-Z27 | 21 | PDUVOR | PDU Voltage Operating Range | 3.7 | 3.2 | 4.2 | V | | 22 | TOB09 | PD | VAPE-Z27 | 22 | PDUCOR | PDU Current Operating Range | 1200 | 850 | 1800 | mA | | 23 | TOB09 | PD | VAPE-Z27 | 23 | PDUWTOR | PDU Wattage Operating Range | 75 | 70 | 80 | W | 24 | TOB09 | PD | VAPE-Z27 | 24 | PDUTCTOF | PDU Temperature Cut-off | 70 | 55 | 65 | C | | 2524 | TOB09 | PD | VAPE-Z27 | 2524 | AIRFLRT | Airflow Rate | 720 | 700 | 740 | L/min | | 2625 | TOB09 | PD | VAPE-Z27 | 2625 | PDUCRCOF | PDU Current Cut-off | 35 | 20 | 50 | mA | | 2726 | TOB09 | PD | VAPE-Z27 | 2726 | INHAERT | Inhaled Aerosol Temperature | 37 | 35 | 40 | C | | 2827 | TOB09 | PD | VAPE-Z27 | 2827 | VENTLTNVENTLTOT | Total Ventilation | 50 | 40 | 60 | % | | 2928 | TOB09 | PD | VAPE-Z27 | 2928 | ELQDVISC | E-Liquid Viscosity | 500 | 75 | 1130 | mPa/s | | 3029 | TOB09 | PD | VAPE-Z27 | 3029 | ELQDVOL | E-liquid Volume | 60 | 10 | 120 | mL | | 3130 | TOB09 | PD | VAPE-Z27 | 3130 | PNUMCNC | Particle Number Concentration | 500 | 108 | 1010 | /cm3 | | 3231 | TOB09 | PD | VAPE-Z27 | 3231 | CTMDDIAM | Count Median Diameter | 200 | 150 | 250 | nm | | 3332 | TOB09 | PD | VAPE-Z27 | 3332 | PM2.5 | Particulate Matter 2.5 | 25 | 12 | 35 | ug/m3 |
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Finally, the Tobacco Product Testing ( PT ) domain is used to represent the actual results of testing the manufactured ENDS product for conformance to the tobacco product design parameters shown in PD above. PTCAT is a required Required variable and is set to "DESIGN PARAMETER TESTING" for all records here. Typically, applicants would submit data on each parameter in multiple replicates. For simplicity of review, only one 1 replicate per parameter is shown. Note that PTREPNUM (repetition number) = 1 for all rows.
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| Row | STUDYID | DOMAIN | SPTOBID | PTSEQ | PTREFID | PTTESTCD | PTTEST | PTTSTCND | PTCAT | PTSCAT | PTORRES | PTORRESU | PTSTRESC | PTSTRESN | PTSTRESU | |
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PTTPT | PTTPTNUM |
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| 1 | TOB09 | PT | VAPE-Z27 | |
| DRWRST | Draw Resistance |
| DESIGN PARAMETER TESTING |
| 91 | mm H2O | 91 | 91 | mm H2O | 1 |
Week 0 | 1 | | 2 | TOB09 | PT | VAPE-Z27 | 2 |
| PUFCNT | Puff Count |
| DESIGN PARAMETER TESTING |
| 309 |
| 309 | 309 |
| 1 |
Week 0 | 1 | | 3 | TOB09 | PT | VAPE-Z27 | 3 |
| CRTVOL | Cartridge Volume |
| DESIGN PARAMETER TESTING |
| 3.09 | mL | 3.09 | 3.09 | mL | 1 |
Week 01 | | 4 | TOB09 | PT | VAPE-Z27 | 4 |
| HTELNUM | Number of Heating Elements |
| DESIGN PARAMETER TESTING |
| 1 |
| 1 | 1 |
| 1 |
Week 0 | 1 | | 5 | TOB09 | PT | VAPE-Z27 | 5 |
| HTELGTH | Heating Element Length |
| DESIGN PARAMETER TESTING |
| 2.97 | mm | 2.97 | 2.97 | mm | 1 |
Week 0 | 1 | | 6 | TOB09 | PT | VAPE-Z27 | 6 |
| HTEDIAM | Heating Element Diameter |
| DESIGN PARAMETER TESTING |
| 3.05 | mm | 3.05 | 3.05 | mm | | | 7 | TOB09 | PT | VAPE-Z27 | 7 |
| HTELRST | Heating Element Resistance |
| DESIGN PARAMETER TESTING |
| 0.77 | ohm | 0.77 | 0.77 | ohm | 1 |
Week 01 | | 8 | TOB09 | PT | VAPE-Z27 | 8 |
| HTELRNG | Heating Element Range |
| DESIGN PARAMETER TESTING |
| 174 | C | 174 | 174 | C |
1 | Week 0 | 1 | | 9 | TOB09 | PT | VAPE-Z27 | 9 |
| HTELCFG | Heating Element Configuration |
| DESIGN PARAMETER TESTING |
| SPIRAL |
| SPIRAL | SPIRAL |
1 | Week 0 |
| 1 | | 10 | TOB09 | PT | VAPE-Z27 | 10 |
| BTVLTORG | Battery Voltage Operating Range |
| DESIGN PARAMETER TESTING |
| 4.6 | V | 4.6 | 4.6 | V | 1 |
Week 0 | 1 | | 11 | TOB09 | PT | VAPE-Z27 | 11 |
| BTCRTORG | Battery Current Operating Range |
| DESIGN PARAMETER TESTING |
| 997 | mAh | 997 | 997 | mAh | 1 |
Week 0 | 1 | | 12 | TOB09 | PT | VAPE-Z27 | 12 |
| BATCAPC | Battery Capacity |
| DESIGN PARAMETER TESTING |
| 1112 | mAh | 1112 | 1112 | mAh |
1 | Week 0 | 1 | | 13 | TOB09 | PT | VAPE-Z27 | 13 |
| BATNOMV | Battery Nominal Voltage |
| DESIGN PARAMETER TESTING |
| 4.18 | V | 4.18 | 4.18 | V | 1 |
Week 01 | | 14 | TOB09 | PT | VAPE-Z27 | 14 |
| BTCRTRT | Battery Current Rating |
| DESIGN PARAMETER TESTING |
| 2488 | mA | 2488 | 2488 | mA |
1 | Week 0 | 1 | | 15 | TOB09 | PT | VAPE-Z27 | 15 |
| BTCHTPL | Battery Charging Temperature Limits |
| DESIGN PARAMETER TESTING |
| 198 | C | 198 | 198 | C | 1 |
Week 01 | | 16 | TOB09 | PT | VAPE-Z27 | 16 |
| BTDCTMPL | Battery Discharge Temperature Limits |
| DESIGN PARAMETER TESTING |
| 19 | C | 19 | 19 | C | 1 |
Week 01 | | 17 | TOB09 | PT | VAPE-Z27 | 17 |
| BTENDCV | Battery End of Discharge Voltage |
| DESIGN PARAMETER TESTING |
| 3.03 | V | 3.03 | 3.03 | V | 1 |
Week 0 | 1 | | 18 | TOB09 | PT | VAPE-Z27 | 18 |
| BTMXCHC | Battery Maximum Charging Current |
| DESIGN PARAMETER TESTING |
| 23.5 | mA | 23.5 | 23.5 | mA |
1 | Week 0 | 1 | | 19 | TOB09 | PT | VAPE-Z27 | 19 |
| BTMXDCC | Battery Maximum Discharging Current |
| DESIGN PARAMETER TESTING |
| 2696 | mA | 2696 | 2696 | mA |
1 | Week 0 | 1 | | 20 | TOB09 | PT | VAPE-Z27 | 20 |
| BTULCHV | Battery Upper Limits Charging Voltage |
| DESIGN PARAMETER TESTING |
| 4.21 | V | 4.21 | 4.21 | V |
1 | Week 0 | 1 | | 21 | TOB09 | PT | VAPE-Z27 | 21 |
| PDUVOR | PDU Voltage Operating Range |
| DESIGN PARAMETER TESTING |
| 3.65 | V | 3.65 | 3.65 | V | 1 |
Week 01 | | 22 | TOB09 | PT | VAPE-Z27 | 22 |
| PDUCOR | PDU Current Operating Range |
| DESIGN PARAMETER TESTING |
| 1202 | mA | 1202 | 1202 | mA | 1 |
Week 0 | 1 | 24 | TOB09 | PT | VAPE-Z27 | 24 | PDUWTOR | PDU Wattage Operating Range | DESIGN PARAMETER TESTING | 75 | W | 75 | 75 | W | 1 | Week 0 | 1 | 25| PDUTCTOF | PDU Temperature Cut-off |
| DESIGN PARAMETER TESTING |
| 69.9 | C | 69.9 | 69.9 | C | 1 |
Week 0 | 1 | 25| 24 |
| AIRFLRT | Airflow Rate |
| DESIGN PARAMETER TESTING |
| 727 | L/min | 727 | 727 | L/min | 1 |
Week 0 | 1 | 26 | 2627| 25 |
| PDUCRCOF | PDU Current Cut-off |
| DESIGN PARAMETER TESTING |
| 34.8 | mA | 34.8 | 34.8 | mA | 1 |
Week 0 | 1 | 27| 26 |
| INHAERT | Inhaled Aerosol Temperature |
| DESIGN PARAMETER TESTING |
| 36.9 | C | 36.9 | 36.9 | C | 1 |
Week 0 | 1 | 28 | 28VENTLTN
| VENTLTOT | Total Ventilation |
| DESIGN PARAMETER TESTING |
| 51 | % | 51 | 51 | % | 1 |
Week 0 | 1 | 29 | 2930| 28 |
| ELQDVISC | E-Liquid Viscosity | Test performed at 20 degrees Celsius | DESIGN PARAMETER TESTING |
| 496 | mPa/s | 496 | 496 | mPa/s | 1 |
Week 0 | 1 | 3031 | | 29 |
| ELQDVOL | E-liquid Volume |
| DESIGN PARAMETER TESTING |
| 60.1 | mL | 60.1 | 60.1 | mL | 1 |
Week 0 | 1 | 31| 30 |
| PNUMCNC | Particle Number Concentration |
| DESIGN PARAMETER TESTING |
| 511 | /cm3 | 511 | 511 | /cm3 | 1 |
Week 0 | 1 | 32 | 3233| 31 |
| CTMDDIAM | Count Median Diameter |
| DESIGN PARAMETER TESTING |
| 202 | nm | 202 | 202 | nm | 1 |
Week 0 | 1 | 33| 32 |
| PM2.5 | Particulate Matter 2.5 |
| DESIGN PARAMETER TESTING |
| 24.4 | ug/m3 | 24.4 | 24.4 | ug/m3 |
1 | Week 0 |
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