Late gadolinium enhancement (LGE) increases over time for patients with DMD. Early onset LGE may be used as a prognostic factor since cardiac function has been shown to decline more rapidly for these patients. (ref: https://publications.aap.org/pediatrics/article/149/1%20Meeting%20Abstracts%20February%202022/325/186143/Early-onset-Late-Gadolinium-Enhancement-Is-a?autologincheck=redirected)[5]
LGE assessments can be done on each of the cardiovascular segments as shown in Figure 1. (ref: https://www.ahajournals.org/doi/full/10.1161/hc0402.102975)[6]
Excerpt Include Figure 1. Left Ventricular Segments Figure 1. Left Ventricular Segments
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For more information on the domains used in this section see:
The SDTMIG is available at https://www.cdisc.org/standards/foundational/sdtmig. |
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