"Cardiomyopathy with systolic heart Cardiorespiratory failure is the leading a common cause of death and lower LVEF is an independent predictor of mortality at younger ages in patients with DMD." (ref: https://openres.ersjournals.com/content/9/5/00176-2023)"Duchenne muscular dystrophy is associated with progressive cardiorespiratory failure, including left ventricular dysfunction." (ref: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941672/)for patients with Duchenne muscular dystrophy (DMD). Current therapies may delay the progression of heart failure for this population. Measuring left ventricular ejection fraction (LVEF) regularly can show the rate of decline in left ventricle function for a patient.[1]
This section illustrates how the results of several systolic function tests, and accompanying data, are represented using the SDTM.
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For more information on the domains used in this section see the SDTMIG v3.4., see:
The SDTMIG is available at https://www.cdisc.org/standards/foundational/sdtmig. |
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