Circumferential and Longitudinal Strain are CMR measurement parameters used to evaluate progression of cardiac dysfunction. This example shows how to represent the findings of these tests the representation of circumferential and longitudinal strain findings in the CV domain. Check with team and CT - these are different than the 17 segments in the other example. Not sure if these can be generalized to the heart or if the locations need to be specific by ventricle (seems like but I am not sure). It may indicate the view of 4 chambers from the left ventricular wall side (left ventricle, 4 -chamber)The sponsor used the "CMRBRANDTYP Feature Tracking" analysis method (CVANMETH).
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| Rows 1-3: | Show circumferential strain using the CMR Brand Type (CMRBRANDTYP) Feature tracking analysis for the left ventricular ventricle base, mid, and apex regions (CVLOC). | | Row 4: | Shows the left ventricular global circumferential strain (CVLOC=LV Global) and (CVTEST=CIRCUMFERENTIAL STRAIN)circumferential strain for the LEFT VENTRICULAR BASAL INFEROSEPTAL SEGMENT. | | Row 5: | Shows the global circumferential strain for the LV Basal Inferoseptal segment (CVLOC= LEFT VENTRICULAR BASAL INFEROSEPTAL SEGMENT). | | Rows 6-8: | Show the longitudinal strain for 4 chamber, 3 chamber, and 2 chamber of the left ventricleviews. | | Row 9: | Shows the left ventricular global longitudinal strain (CVLOC=LV Global) and (CVTEST=LONGITUDINAL STRAIN)longitudinal strain for the LEFT VENTRICULAR BASAL INFEROSEPTAL SEGMENT. | | Row 10: | Shows global longitudinal strain for the left ventricular, 4 chamber, basal inferoseptal segment. |
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Row | STUDYID | DOMAIN | USUBJID | CVSEQ | CVTESTCD | CVTEST | CVORRES | CVORRESU | CVSTRESC | CVSTRESN | CVSTRESU | CVLOC | CVMETHOD | CVANMETH | CVLOBFXL | VISITNUM | VISIT | CVDTC |
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| 1 | DMD-CLS | CV | DMD-CLS-01-401 | 1 | CFSTRAIN |
CIRCUMFERENTIAL STRAIN| Circumferential Strain | | % | | -9 | % | HEART, LEFT |
VENTRICULAR CARDIAC MAGNETIC RESONANCE IMAGING| MRI | CMRBRANDTYP Feature Tracking |
| 1 | VISIT 1 | 2023-09-01 |
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| | 2 | DMD-CLS | CV | DMD-CLS-01-401 | 2 | CFSTRAIN |
CIRCUMFERENTIAL STRAIN| Circumferential Strain | | % | | -12 | % | HEART, LEFT |
VENTRICULAR CARDIAC MAGNETIC RESONANCE IMAGING| MRI | CMRBRANDTYP Feature tracking |
| 1 | VISIT 1 | 2023-09-01 |
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| | 3 | DMD-CLS | CV | DMD-CLS-01-401 | 3 | CFSTRAIN |
CIRCUMFERENTIAL STRAIN| Circumferential Strain | | % | | -10 | % | HEART, LEFT |
VENTRICULAR CARDIAC MAGNETIC RESONANCE IMAGING| MRI | CMRBRANDTYP Feature tracking |
| 1 | VISIT 1 | 2023-09-01 |
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| | 4 | DMD-CLS | CV | DMD-CLS-01-401 | 4 | CFSTRAIN |
CIRCUMFERENTIAL STRAIN101010% GLOBAL| BASAL INFEROSEPTAL SEGMENT | MRI |
CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | VISIT 1 | 2023-09-01 |
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| | 5 | DMD-CLS | CV | DMD-CLS-01-401 | 5 |
CFSTRAIN | | GCS | Global Circumferential Strain |
CIRCUMFERENTIAL STRAIN121212LEFT VENTRICULAR BASAL INFEROSEPTAL SEGMENT | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | VISIT 1 | 2023-09-01 |
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| | 6 | DMD-CLS | CV | DMD-CLS-01-401 | 6 |
LNGSTRAINLONGITUDINAL STRAIN, 4 CHAMBERCARDIAC MAGNETIC RESONANCE IMAGING | MRI | CMRBRANDTYP Feature Tracking |
| 1 | VISIT 1 | 2023-09-01 |
| 4-CHAMBER | | 7 | DMD-CLS | CV | DMD-CLS-01-401 | 7 | LOSTRAIN |
LONGITUDINAL STRAIN, 3 CHAMBERCARDIAC MAGNETIC RESONANCE IMAGING | MRI | CMRBRANDTYP Feature tracking |
| 1 | VISIT 1 | 2023-09-01 |
| 3-CHAMBER | | 8 | DMD-CLS | CV | DMD-CLS-01-401 | 8 | LOSTRAIN |
LONGITUDINAL STRAIN, 2 CHAMBERCARDIAC MAGNETIC RESONANCE IMAGING | MRI | CMRBRANDTYP Feature tracking |
| 1 | VISIT 1 | 2023-09-01 |
| 2-CHAMBER | | 9 | DMD-CLS | CV | DMD-CLS-01-401 | 9 | LOSTRAIN |
LONGITUDINAL STRAIN181818 GLOBAL| BASAL INFEROSEPTAL SEGMENT | MRI |
CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | VISIT 1 | 2023-09-01 |
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| | 10 | DMD-CLS | CV | DMD-CLS-01-401 | 10 |
LOSTRAIN | | LGS | Global Longitudinal Strain |
LONGITUDINAL STRAIN141414LEFT VENTRICULAR 4 CHAMBER BASAL INFEROSEPTAL SEGMENT | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | VISIT 1 | 2023-09-01 |
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| Variable | Label | Type | Role | Origin |
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| Imaging View | text | Non-standard Record Qualifier | CRF |
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