Request | Notes | Status |
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Model system serology example | Requested by Dan and Joleen. | Status |
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colour | Yellow |
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title | In Process |
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Fc receptor definition
Fc receptor is a antibody receptor involved in antigen recognition which is located at the membrane of certain immune cells including B lymphocytes, natural killer cells, macrophages, neutrophils, and mast cells. Such receptors recognize Fc fragment of antibodies and that is the name of Fc receptor derived from. Fc receptors binding to antibodies that are attached to infected cells or invading pathogens contributes to the protective functions of the immune system.Their activity stimulates phagocytic or cytotoxic cells to destroy microbes, or infected cells by antibody-mediated phagocytosis or antibody-dependent cell-mediated cytotoxicity.
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hi1style | yellow |
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hi1 | column ISBDAGNT |
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tableid | IS table 1 |
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| Row | STUDYID | DOMAIN | USUBJID | SPDEVID | EXAMPLES (not a variable)ISSEQ | ISTESTCD | ISTEST | ISBDAGNT | Fc-Mediated Antibody Effectors/ISFCABEF | ISTSTDTL | ISORRES | ISORRESU | ISSTRESC | ISMETHOD | ISDTC |
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1 | ABC | IS | ABC-01-201 | ABC001 | example 1 |
| Functional IgG Antibody | Influenza A H1 Hemagglutinin | Fc Gamma Receptor IIIa Polymorphism 158V (or Other types of Fc receptors) |
| 36920 | mdFI |
| Luminex? | 2013-08-26 | 1 | ABC | IS | ABC-01-201 | ABC001 | example 2 |
| Functional IgG Antibody | Influenza A H1 Hemagglutinin | Complement Protein System (i.e. Complement 3B, complement 3A, Complement Attack Complex) |
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| 1 | ABC | IS | ABC-01-201 | ABC001 | example 3 |
| Functional IgG Antibody | Influenza A H1 Hemagglutinin | Cells (i.e. Neutrophils/Macrophages), for cell-dependent immune response | Opsonization Index (Ine to have to look at the test detail values) |
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| Antibody-Dependent Cellular Phagocytosis ADCP); Antibody-dependent cellular cytotoxicity (ADCC) |
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