Page History

This is an example showing the report table, trial design, and results from a study's in vitro bacterial reverse mutation test 

Jira
showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-505

test using 4 different amino acid-requiring strains of S. typhimurium and 1 strain of E. coli to detect point mutations. 

Image Removed

Image Removed

Image Added

Expand
title Report Table for Example Study 8325064
This table shows the assay results for study 8325064, test article TA1, and 3 strains of salmonella (TA98, TA100, and TA1535) at varying concentrations.  For For brevity, the remaining tables (e.g., additional strains, samples prepared without metabolic activation) are not included. Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-506 For  For ease of reference in the table below, each row has been labeled in the right-hand margin with the applicant-defined trial set label (e.g., SetA).  For brevity, only the four bolded sets are represented in the following example datasets. jira Image Added
showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-453

This example Trial This example Trial Summary (TS) dataset

Jira
showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-481

, shows many informational fields that provide context at the study level.   

Jira
showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-663

 

Jira
showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-664

at the study level.   

Dataset wrap

Rowcaps Rows 1-2: Show 2 records for TSPARMCD = "GLPTYP", using TSSEQ to indicate multiple records, Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-366 since  since both GLP types apply for this  study.  Row 3: Shows that this study was conducted as a GLP study. Rows 4-5: Show the study start date and study title. Rows 6-7: Show the version of SEND Implementation Guide and version of Controlled Terminology used in this study. Row 8: Shows the applicant's organization. Row 9: Shows that the applicant's study reference ID is not applicable. Rows 10-13: Show that TSGRPID has been used to link records (name, location, country) related to the test facility (TSGRPID=1). The study director is associated with the test facility. Rows 14-16: Show that TSGRPID (TSGRPID=4) has been used to link the information on the testing guideline followed on this study (TSTGDNAM, TSTGDORG, TSTGDVER). Row 17: Shows the study type for this study. Row 18: Shows that this study includes a Bacterial Reverse Mutation Assay. Rows 19-27: Show that TSGRPID (TSGRPID = 2) has been used to link the information for 1 species (salmonella) with the 4 different strains and cell lines that are tested in this  study. Rows 28-30: Show that TSGRPID (TSGRPID = 3) has been used to link the information for 1 species (E. coli) with the strain and cell line that is tested in this study. Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-665 line that is tested in this study. Dataset2 TOBA-482 Row STUDYID DOMAIN TSSEQ TSGRPID TSPARMCD TSPARM TSVAL TSVALNF 1 8325064 TS 1 GLPTYP Good Laboratory Practice Type FDA 2 8325064 TS 2 GLPTYP Good Laboratory Practice Type OECD 3 8325064 TS 1 GLPFL GLP Flag N 4 8325064 TS 1 STSTDTC Study Start Date 2015-07-29 5 8325064 TS 1 STITLE Study Title The Bacterial Reverse Mutation Test, Study 8325064-1 6 8325064 TS 1 SNDIGVER SEND Implementation Guide Version TOBACCO IMPLEMENTATION GUIDE VERSION 1.0 7 8325064 TS 1 SNDCTVER SEND Controlled Terminology Version SEND Terminology 2021-09-30 8 8325064 TS 1 APPLCNT Applicant Organization Example Applicant Inc. 9 8325064 TS 1 APREFID Applicant's Study Reference ID NOT APPLICABLE 10 8325064 TS 1 1 TSTFNAM Test Facility Name Example Tox Lab Name 11 8325064 TS 1 1 TSTFLOC Test Facility Location 10 Somewhere Street, Montgomery, AL 10000 12 8325064 TS 1 1 TFCNTRY Test Facility Country USA 13 8325064 TS 1 1 STDIR Study Director Dr. R. Smith 14 8325064 TS 1 4 TSTGDNAM Testing Guideline Name Test NO. 471 15 8325064 TS 1 4 TSTGDORG Testing Guideline Organization OECD 16 8325064 TS 1 4 TSTGDVER Testing Guideline Version 2020-06-29 17 8325064 TS 1 SSTYP Study Type GENOTOXICITY IN VITRO 18 8325064 TS 1 GNTXAID Genetic Toxicology Assay Identifier AMES 19 8325064 TS 1 2 SPECIES Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-484 Species SALMONELLA TYPHIMURIUM 20 8325064 TS 1 2 STRAIN Strain/Substrain TA98 21 8325064 TS 2 2 STRAIN Strain/Substrain TA100 22 8325064 TS 3 2 STRAIN Strain/Substrain TA1535 23 8325064 TS 4 2 STRAIN Strain/Substrain TA1537 24 8325064 TS 1 2 CELLLN Cell Line TA 98 hisD3052; rfa-; uvrB- 25 8325064 TS 2 2 CELLLN Cell Line TA 100 hisG46; rfa-; uvrB- 26 8325064 TS 3 2 CELLLN Cell Line TA 1535 hisG46; rfa-; uvrB- 27 8325064 TS 4 2 CELLLN Cell Line TA 1537 hisC3076; rfa-; uvrB- 28 8325064 TS 2 3 SPECIES Species 3 SPECIES Species ESCHERICHIA COLIESCHERICHIA COLI Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key 29 8325064 TS 5 3 STRAIN Strain/Substrain WP2 uvrA pKM101 30 8325064 TS 5 3 CELLLN Cell Line trpE uvrA

This example Trial Set (TX) dataset shows information about the test conditions for SetA and SetR in this study. For brevity, the dataset does not show information for SetF, SetG, or any other sets.  

Jira
showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-483

A fully formed TX dataset for this example study would include information about the test conditions for all sets. 

...

Dataset wrap
Name tx
Rowcaps TOBA-666study 8325064. Rows 1-22: Show trial set parameters and trial set values that are the test conditions specific to set SetA which is the vehicle control (i.e., Strain of TA98, vehicle control with concentration value of 0). SetA is associated with the first row, labeled "SetA", in the report table for example study 8325064. Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key Rows 23-44: Show trial set parameters and trial set values that comprise the test conditions for the set SetF which is the strain of TA98 with a concentration value of 500 µg/plate. SetF is associated with the sixth row, labeled "SetF", in the report table for example study 8325064. Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-667 Rows 45-66: Show trial set parameters and trial set values that comprise the test conditions for the set SetG which is the strain of TA98 with a concentration value of 1600 µg/plate. SetG is associated with the seventh row, labeled "SetG", in the report table for example study 8325064. Rows 67-88: Show trial set parameters and trial set values that comprise the test conditions for the set SetR which is the strain of TA100, positive control with a concentration value of 2 µg/plate. SetR is associated with the eighteenth row, labeled "SetR", in the report table for example study 8325064. Dataset2   Row STUDYID DOMAIN SETCD SET TXSEQ TXPARMCD TXPARM TXVAL 1 8325064 TX SetA A-TA98-C0 1 SPECIES Species SALMONELLA TYPHIMURIUM 2 8325064 TX SetA A-TA98-C0 2 IVTDMIN In vitro Treatment Duration Minimum 71.5 3 8325064 TX SetA A-TA98-C0 3 IVTDTRG In vitro Treatment Duration Target 72 4 8325064 TX SetA A-TA98-C0 4 IVTDMAX In vitro Treatment Duration Maximum 72.5 5 8325064 TX SetA A-TA98-C0 5 IVTDU In vitro Treatment Duration Unit HOURS 6 8325064 TX SetA A-TA98-C0 6 INCBTMP Incubation Temperature 37 7 8325064 TX SetA A-TA98-C0 7 INCBTMPU Incubation Temperature Unit C 8 8325064 TX SetA A-TA98-C0 8 ATMRHP Atmospheric Relative Humidity Percent 50 9 8325064 TX SetA A-TA98-C0 9 ATMCO2P Atmospheric CO2 Percent 5 10 8325064 TX SetA A-TA98-C0 10 SPTOBID Applicant-defined tobacco identifier CIG01a 11 8325064 TX SetA A-TA98-C0 11 EXPTYP Exposure Type Submerged 12 8325064 TX SetA A-TA98-C0 12 SAMTYP Sample Type Total Particulate Matter in PBS 13 8325064 TX SetA A-TA98-C0 13 APDEVID Applicant-defined device identifier PUFFMASTER3K 14 8325064 TX SetA A-TA98-C0 14 SMKRGM Smoking Regimen NON-INTENSE REGIMEN 15 8325064 TX SetA A-TA98-C0 15 STRAIN Strain/Substrain TA98 16 8325064 TX SetA A-TA98-C0 16 MTACTIND Metabolic Activating Agent Name NOT APPLICABLE 17 8325064 TX SetA A-TA98-C0 17 METACTFL Presence of Metabolic Activation Flag N 18 8325064 TX SetA A-TA98-C0 18 ITVNAM Intervention Article Name DMSO 19 8325064 TX SetA A-TA98-C0 19 ITVTYPE Intervention Article Type VEHICLE 20 8325064 TX SetA A-TA98-C0 20 ITVCONC Intervention Article Concentration 100 21 8325064 TX SetA A-TA98-C0 21 ITVCONCU Intervention Article Concentration Unit % 22 8325064 TX SetA A-TA98-C0 22 TRTV Treatment Vehicle DMSO 23 8325064 TX SetF F-TA98-C500 23 SPECIES Species SALMONELLA TYPHIMURIUM 24 8325064 TX SetF F-TA98-C500 24 IVTDMIN In vitro Treatment Duration Minimum 71.5 25 8325064 TX SetF F-TA98-C500 25 IVTDTRG In vitro Treatment Duration Target 72 26 8325064 TX SetF F-TA98-C500 26 IVTDMAX In vitro Treatment Duration Maximum 72.5 27 8325064 TX SetF F-TA98-C500 27 IVTDU In vitro Treatment Duration Unit HOURS 28 8325064 TX SetF F-TA98-C500 28 INCBTMP Incubation Temperature 37 29 8325064 TX SetF F-TA98-C500 29 INCBTMPU Incubation Temperature Unit C 30 8325064 TX SetF F-TA98-C500 30 ATMRHP Atmospheric Relative Humidity Percent 50 31 8325064 TX SetF F-TA98-C500 31 ATMCO2P Atmospheric CO2 Percent 5 32 8325064 TX SetF F-TA98-C500 32 SPTOBID Applicant-defined tobacco identifier CIG01a 33 8325064 TX SetF F-TA98-C500 33 EXPTYP Exposure Type Submerged 34 8325064 TX SetF F-TA98-C500 34 SAMTYP Sample Type Total Particulate Matter in PBS 35 8325064 TX SetF F-TA98-C500 35 APDEVID Applicant-defined device identifier PUFFMASTER3K 36 8325064 TX SetF F-TA98-C500 36 SMKRGM Smoking Regimen NON-INTENSE REGIMEN 37 8325064 TX SetF F-TA98-C500 37 STRAIN Strain/Substrain TA98 38 8325064 TX SetF F-TA98-C500 38 MTACTIND Metabolic Activating Agent Name NOT APPLICABLE 39 8325064 TX SetF F-TA98-C500 39 METACTFL Presence of Metabolic Activation Flag N 40 8325064 TX SetF F-TA98-C500 40 ITVNAM Intervention Article Name TA1 41 8325064 TX SetF F-TA98-C500 41 ITVTYPE Intervention Article Type PRODUCT 42 8325064 TX SetF F-TA98-C500 42 ITVCONC Intervention Article Concentration 500 43 8325064 TX SetF F-TA98-C500 43 ITVCONCU Intervention Article Concentration Unit ug/plate 44 8325064 TX SetF F-TA98-C500 44 TRTV Treatment Vehicle DMSO 45 8325064 TX SetG G-TA98-C1600 45 SPECIES Species SALMONELLA TYPHIMURIUM 46 8325064 TX SetG G-TA98-C1600 46 IVTDMIN In vitro Treatment Duration Minimum 71.5 47 8325064 TX SetG G-TA98-C1600 47 IVTDTRG In vitro Treatment Duration Target 72 48 8325064 TX SetG G-TA98-C1600 48 IVTDMAX In vitro Treatment Duration Maximum 72.5 49 8325064 TX SetG G-TA98-C1600 49 IVTDU In vitro Treatment Duration Unit HOURS 50 8325064 TX SetG G-TA98-C1600 50 INCBTMP Incubation Temperature 37 51 8325064 TX SetG G-TA98-C1600 51 INCBTMPU Incubation Temperature Unit C 52 8325064 TX SetG G-TA98-C1600 52 ATMRHP Atmospheric Relative Humidity Percent 50 53 8325064 TX SetG G-TA98-C1600 53 ATMCO2P Atmospheric CO2 Percent 5 54 8325064 TX SetG G-TA98-C1600 54 SPTOBID Applicant-defined tobacco identifier CIG01a 55 8325064 TX SetG G-TA98-C1600 55 EXPTYP Exposure Type Submerged 56 8325064 TX SetG G-TA98-C1600 56 SAMTYP Sample Type Total Particulate Matter in PBS 57 8325064 TX SetG G-TA98-C1600 57 APDEVID Applicant-defined device identifier PUFFMASTER3K 58 8325064 TX SetG G-TA98-C1600 58 SMKRGM Smoking Regimen NON-INTENSE REGIMEN 59 8325064 TX SetG G-TA98-C1600 59 STRAIN Strain/Substrain TA98 60 8325064 TX SetG G-TA98-C1600 60 MTACTIND Metabolic Activating Agent Name NOT APPLICABLE 61 8325064 TX SetG G-TA98-C1600 61 METACTFL Presence of Metabolic Activation Flag N 62 8325064 TX SetG G-TA98-C1600 62 ITVNAM Intervention Article Name TA1 63 8325064 TX SetG G-TA98-C1600 63 ITVTYPE Intervention Article Type Product 64 8325064 TX SetG G-TA98-C1600 64 ITVCONC Intervention Article Concentration 1600 65 8325064 TX SetG G-TA98-C1600 65 ITVCONCU Intervention Article Concentration Unit ug/plate 66 8325064 TX SetG G-TA98-C1600 66 TRTV Treatment Vehicle DMSO 67 8325064 TX SetR R-TA100-C2 67 SPECIES Species SALMONELLA TYPHIMURIUM 68 8325064 TX SetR R-TA100-C2 68 IVTDMIN In vitro Treatment Duration Minimum 71.5 69 8325064 TX SetR R-TA100-C2 69 IVTDTRG In vitro Treatment Duration Target 72 70 8325064 TX SetR R-TA100-C2 70 IVTDMAX In vitro Treatment Duration Maximum 72.5 71 8325064 TX SetR R-TA100-C2 71 IVTDU In vitro Treatment Duration Unit HOURS 72 8325064 TX SetR R-TA100-C2 72 INCBTMP Incubation Temperature 37 73 8325064 TX SetR R-TA100-C2 73 INCBTMPU Incubation Temperature Unit C 74 8325064 TX SetR R-TA100-C2 74 ATMRHP Atmospheric Relative Humidity Percent 50 75 8325064 TX SetR R-TA100-C2 75 ATMCO2P Atmospheric CO2 Percent 5 76 8325064 TX SetR R-TA100-C2 76 SPTOBID Applicant-defined tobacco identifier CIG01a 77 8325064 TX SetR R-TA100-C2 77 EXPTYP Exposure Type Submerged 78 8325064 TX SetR R-TA100-C2 78 SAMTYP Sample Type Total Particulate Matter in PBS 79 8325064 TX SetR R-TA100-C2 79 APDEVID Applicant-defined device identifier PUFFMASTER3K 80 8325064 TX SetR R-TA100-C2 80 SMKRGM Smoking Regimen NON-INTENSE REGIMEN 81 8325064 TX SetR R-TA100-C2 81 STRAIN Strain/Substrain TA100 82 8325064 TX SetR R-TA100-C2 82 MTACTIND Metabolic Activating Agent Name NOT APPLICABLE 83 8325064 TX SetR R-TA100-C2 83 METACTFL Presence of Metabolic Activation Flag N 84 8325064 TX SetR R-TA100-C2 84 ITVNAM Intervention Article Name NaN3 85 8325064 TX SetR R-TA100-C2 85 ITVTYPE Intervention Article Type Positive Control 86 8325064 TX SetR R-TA100-C2 86 ITVCONC Intervention Article Concentration 2 87 8325064 TX SetR R-TA100-C2 87 ITVCONCU Intervention Article Concentration Unit ug/plate 88 8325064 TX SetR R-TA100-C2 88 TRTV Treatment Vehicle DMSO

REFID values are defined by the applicant to uniquely identify the observational unit within an experimental unit. In the simplified diagram of an assay procedure (below), the test tube that contains the possible mutagen is an example of an entity that would have a REFID indicating information at the level of trial set. The petri plate created from that test tube and used to count revertant numbers is an example of an entity that would be at an observational level. level. 

This picture does not depict the more complicated procedures, This picture does not depict the more complicated procedures,

Jira
showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-370

trial sets, or observational units for the example study. For study 8325064, the applicant chose to define the REFIDs at the trial set level with a single character (e.g., A, F, G, R) and chose to define REFIDs at the observational level based on the location of each tube in 1 of multiple exposure/incubation plates (e.g, 6_1 for plate 6, position 1). 

...

Dataset wrap
Name relref
Rowcaps Row 1: Shows the value of REFID=A. This REFID refers to the trial set with a SETCD of "SetA", as defined in the TX dataset. LEVEL=1 and LVLDESC="EXPERIMENTAL UNIT/TRIAL SET". TRIAL SET indicates this identifier relates to the entire trial set. EXPERIMENTAL UNIT indicates this identifier received the intervention article, DMSO.  Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-489 Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-458 . TRIAL SET indicates this identifier relates to the entire trial set. EXPERIMENTAL UNIT indicates this identifier received the intervention article, DMSO. Rows 2-6: Show the values of 5 observational units (1_1 through 1_5) that are within the parent experimental unit, REFID=A. Row 7:  Shows the value of REFID=F. This REFID refers to the trial set with a SETCD of "SetF", as defined in the TX dataset. LEVEL=1 and LVLDESC="EXPERIMENTAL UNIT/TRIAL SET". TRIAL SET indicates this identifier relates to the entire trial set. EXPERIMENTAL UNIT indicates this identifier received the intervention article, TA1. Rows 8-10: Show the values of 3 observational units (6_1 through 6_3) that are within the parent experimental unit, REFID=F. Row 11: Shows the value of REFID=G. This REFID refers to the trial set with a SETCD of "SetG", as defined in the TX dataset. LEVEL=1 and LVLDESC="EXPERIMENTAL UNIT/TRIAL SET". TRIAL SET indicates this identifier relates to the entire trial set. EXPERIMENTAL UNIT indicates this identifier received the intervention article, TA1. Rows 12-14: Show the values of 3 observational units (7_1 through 7_3) that are within the parent experimental unit, REFID=G. Row 15: Shows the value of REFID=R. This REFID refers to the trial set with a SETCD of "SetG", as defined in the TX dataset. LEVEL=1  and LVLDESC="EXPERIMENTAL UNIT/TRIAL SET". TRIAL SET indicates this identifier relates to the entire trial set. EXPERIMENTAL UNIT indicates this identifier received the intervention article, NaN3. Rows 16-18: Show the values of 3 observational units (18_1 through 18_3) that are within the parent experimental unit, REFID=R. Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-668 parent experimental unit, REFID=R. Dataset2 tableid relref.xpt Row STUDYID SETCD REFID PARENT LEVEL LVLDESC 1 8325064 SetA A 1 EXPERIMENTAL UNIT/TRIAL SET 2 8325064 SetA 1_1 A 2 OBSERVATIONAL UNIT 3 8325064 SetA 1_2 A 2 OBSERVATIONAL UNIT 4 8325064 SetA 1_3 A 2 OBSERVATIONAL UNIT 5 8325064 SetA 1_4 A 2 OBSERVATIONAL UNIT 6 8325064 SetA 1_5 A 2 OBSERVATIONAL UNIT 7 8325064 SetF F 1 EXPERIMENTAL UNIT/TRIAL SET 8 8325064 SetF 6_1 F 2 OBSERVATIONAL UNIT 9 8325064 SetF 6_2 F 2 OBSERVATIONAL UNIT 10 8325064 SetF 6_3 F 2 OBSERVATIONAL UNIT 11 8325064 SetG G 1 EXPERIMENTAL UNIT/TRIAL SET 12 8325064 SetG 7_1 G 2 OBSERVATIONAL UNIT 13 8325064 SetG 7_2 G 2 OBSERVATIONAL UNIT 14 8325064 SetG 7_3 G 2 OBSERVATIONAL UNIT 15 8325064 SetR R 1 EXPERIMENTAL UNIT/TRIAL SET 16 8325064 SetR 18_1 R 2 OBSERVATIONAL UNIT 17 8325064 SetR 18_2 R 2 OBSERVATIONAL UNIT 18 8325064 SetR 18_3 R 2 OBSERVATIONAL UNIT

Jira
showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-454

Dataset wrap
Name gt
Rowcaps Rows 1-5: Show the number of revertant colonies per plate collected for each of 5 observational units, GTREFID=1_1 through 1_5 (see description in the RELREF dataset). Rows 6, 7: Show summary values collected (mean, standard deviation) for GTREFID=A that apply to the entire trial set, SetA, as indicated by LEVEL=1 and LVLDESC=TRIAL SET for this REFID as shown in the RELREF dataset.  Rows 8-13: Revertent colonies were counted for each of 3 plates/observational units (GTREFID=6_1 through 6_3) and each value is associated with a record to show a postfix code of "V" (Very thin background bacterial lawn). Rows 14-16: Show summary values collected (mean, standard deviation, fold increase) for GTREFID=F that apply to the entire trial set, SetF, as indicated by LEVEL=1 and LVLDESC=TRIAL SET for this REFID in the RELREF dataset.  Rows 17-19: Show 3 plates/observational units (GTREFID=7_1 through 7_3) where no revertant colonies were counted due to too much cytotoxicity and a postfix code of "T".  Jira showSummary false server Issue Tracker (JIRA) columnIds issuekey,summary,issuetype,created,updated,duedate,assignee,reporter,priority,status,resolution columns key,summary,type,created,updated,due,assignee,reporter,priority,status,resolution serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-668 Rows 20-22: Show the number of revertant colonies per plate collected for each of 3 observational units (GTREFID=18_1 through 18_3). Rows 23-25: Show summary values collected (mean, standard deviation, fold increase) for GTREFID=R that apply to the entire trial set, SetR, as indicated by LEVEL=1 and LVLDESC=TRIAL SET for this REFID in the RELREF dataset.  Dataset2 TOBA-487 Row STUDYID DOMAIN GTSEQ GTREFID GTTESTCD GTTEST GTORRES GTORRESU GTCOLSRT GTSTRESC GTSTRESN GTSTRESU GTSTAT GTREASND GTMETHOD GTDTC 1 8325064 GT 1 1_1 RPP Revertant Colony Numbers Per Plate 26 26 26 Jira showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key INSTRUMENT COUNTED 2015-08-03 2 8325064 GT 2 1_2 RPP Revertant Colony Numbers Per Plate 35 35 35 INSTRUMENT COUNTED 2015-08-03 3 8325064 GT 3 1_3 RPP Revertant Colony Numbers Per Plate 39 39 39 INSTRUMENT COUNTED 2015-08-03 4 8325064 GT 4 1_4 RPP Revertant Colony Numbers Per Plate 35 35 35 INSTRUMENT COUNTED 2015-08-03 5 8325064 GT 5 1_5 RPP Revertant Colony Numbers Per Plate 30 30 30 INSTRUMENT COUNTED 2015-08-03 6 8325064 GT 6 A RPP Revertant Colony Numbers Per Plate 33.0 MEAN 33.0 33.0 2015-08-03 7 8325064 GT 7 A RPP Revertant Colony Numbers Per Plate 5.0 STANDARD DEVIATION 5.0 5.0 2015-08-03 8 8325064 GT 8 6_1 RPP Revertant Colony Numbers Per Plate 8 8 8 MANUALLY COUNTED 2015-08-03 9 8325064 GT 9 6_1 CYTOTOX Cytotoxicity Very thin background bacterial lawn V 2015-08-03 10 8325064 GT 10 6_2 RPP Revertant Colony Numbers Per Plate 10 10 10 MANUALLY COUNTED 2015-08-03 11 8325064 GT 11 6_2 CYTOTOX Cytotoxicity Very thin background bacterial lawn V 2015-08-03 12 8325064 GT 12 6_3 RPP Revertant Colony Numbers Per Plate 12 12 12 MANUALLY COUNTED 2015-08-03 13 8325064 GT 13 6_3 CYTOTOX Cytotoxicity Very thin background bacterial lawn V 2015-08-03 14 8325064 GT 14 F RPPMEAN Mean Rev Colony Num Per Plate 10.0 MEAN 10.0 10.0 2015-08-03 15 8325064 GT 15 F RPPSTDDV Std Dev Rev Colony Num Per Plate 2.0 STANDARD DEVIATION 2.0 2.0 2015-08-03 16 8325064 GT 16 F RPPFLDIC Fold Increase Rev Colony Num Per Plate 0.3 FOLD INCREASE 0.3 0.3 2015-08-03 17 8325064 GT 17 7_1 CYTOTOX Cytotoxicity Toxic No Revertant Colonies T NOT DONE TOO MUCH CYTOTOXICITY 2015-08-03 18 8325064 GT 18 7_2 CYTOTOX Cytotoxicity Toxic No Revertant Colonies T NOT DONE TOO MUCH CYTOTOXICITY 2015-08-03 19 8325064 GT 19 7_3 CYTOTOX Cytotoxicity Toxic No Revertant Colonies T NOT DONE TOO MUCH CYTOTOXICITY 2015-08-03 20 8325064 GT 20 18_1 RPP Revertant Colony Numbers Per Plate 812 812 812 INSTRUMENT COUNTED 2015-08-03 21 8325064 GT 21 18_2 RPP Revertant Colony Numbers Per Plate 912 912 912 INSTRUMENT COUNTED 2015-08-03 22 8325064 GT 22 18_3 RPP Revertant Colony Numbers Per Plate 839 839 839 INSTRUMENT COUNTED 2015-08-03 23 8325064 GT 23 R RPPMEAN Mean Rev Colony Num Per Plate 854.3 MEAN 854.3 854.3 2015-08-03 24 8325064 GT 24 R RPPSTDDV Std Dev Rev Colony Num Per Plate 51.7 STANDARD DEVIATION 51.7 51.7 2015-08-03 25 8325064 GT 25 R RPPFLDIC Fold Increase Rev Colony Num Per Plate 6.4 FOLD INCREASE 6.4 6.4 2015-08-03