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Question: Can we expand the scope of NHOID in this case? Why was the variable scope limited to "observations about the non-host microbe" in the first place, what were/are the concerns?Can NHOID be used for instances where assessments are conducted to assess direct subject immune responses to a microbe or microbial-derived products via vaccination or antigen-stimulation tests, where NHOID can be used to describe more in detail the microbial taxonomic level information? Any concerns? This scope expansion can be devalued case by case be limited for IS for now (because we have only seen use-cases in IS).

Example 1: Without NHOID, in the example below, all you know is that two types of vaccine-delivered RSV antigens had successfully stimulated antibody responses in this subject. Where do you map the info that the antibody targets (in ISBDAGNT), HUMAN RESPIRATORY SYNCYTIAL VIRUS-PROTEIN B, and HUMAN RESPIRATORY SYNCYTIAL VIRUS-PROTEIN Z) , are actually from two different strains of RSV virus?

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