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This example is currently in draft.

Description of the context of the example for colleagues:

This example shows findings from an assessment of the unique pattern of allelic variation in genes of human leukocyte antigens (HLA), for purposes such as selecting cell, tissue and organ donors, diagnosing autoimmune diseases, determining the risk of adverse drug reactions, or to guide immunotherapies. An arbitrary identifier for the allele is represented in GFCOPYID. Patterns of HLA allele sequences are reported as short codes from a publicly available reference database that identifies the sequence in the database.  

Patterns of HLA sequence are reported as short code from a publicly available reference database that corresponds to the sequence recorded in the database.  

Assessment findings are reported as HLA allele names defined by a nomenclature from a publicly available registry.

Assessment findings are reported as HLA allele names constructed using publicly available a nomenclature.

In general, findings from assessments HLA allelic types may be reported in formats defined in publicly available reference databases. In this example, 

In general, findings from assessments HLA allelic types may be reported defined codes in publicly available reference databases. In this example, 

In general, findings from assessments HLA allelic types may be reported defined codes in publicly available reference databases. In this example, 

Vendor is using a public reference. e

An assessment of the unique pattern of sequence variation of one to many loci associated with a normal or abnormal biological process.

Findings from assessments are reported a

Nomenclature for Factors of the HLA System

Nomenclature of HLA Alleles

Each HLA allele name has a unique number corresponding to up to four sets of digits separated by colons. The length of the allele designation is dependent on the sequence of the allele and that of its nearest relative. All alleles receive at least a four digit name, which corresponds to the first two sets of digits, longer names are only assigned when necessary.

HLA Nomenclature @ hla.alleles.org

https://bioinformatics.bethematchclinical.org/hla-resources/allele-codes/allele-code-lists/

An assessment of the unique pattern of sequence variation of one to many loci associated with a normal or abnormal biological process.

Dataset wrap
Namegf
Rowcaps
Rows 1-9, 11, 15-16:

Show the characterization of the unique pattern of sequence variation for the allele of the HLA gene of interest represented in GFSYM.

Rows 10, 12-14:Show attempted assessments for which results could not be generated due to sequence overlap with the detected DRB1 allele. 
Dataset2
tableidgf
Row #STUDYIDDOMAINUSUBJIDGFSEQGFREFIDGFTESTCDGFTESTGFTSTDTLGFORRESGFSYMGFSYMTYPGFCOPYIDGFSTATGFREASNDGFNAMGFSPECGFMETHODVISITNUMVISITVISITDYGFDTCGFDY
1Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEA*02:TSXZHLA-AGENE WITH PROTEIN PRODUCT1

ACME GenomicsDNASANGER SEQUENCING-1SCREENING-19/16/2023-2
2Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEA*03:ABSAXHLA-AGENE WITH PROTEIN PRODUCT2

ACME GenomicsDNASANGER SEQUENCING




3Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEB*18:TXYFHLA-BGENE WITH PROTEIN PRODUCT1

ACME GenomicsDNASANGER SEQUENCING




4Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEB*38:01HLA-BGENE WITH PROTEIN PRODUCT2

ACME GenomicsDNASANGER SEQUENCING




5Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEC*07:AAEPNHLA-CGENE WITH PROTEIN PRODUCT1

ACME GenomicsDNASANGER SEQUENCING




6Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEC*12:AAGWEHLA-CGENE WITH PROTEIN PRODUCT2

ACME GenomicsDNASANGER SEQUENCING




6Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEDRB1*07:ACEUAHLA-DRB1GENE WITH PROTEIN PRODUCT1

ACME GenomicsDNASANGER SEQUENCING




7Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEDRB1*14:ABZZVHLA-DRB1GENE WITH PROTEIN PRODUCT2

ACME GenomicsDNASANGER SEQUENCING




9Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEDRB3*01:XXHLA-DRB3GENE WITH PROTEIN PRODUCT1

ACME GenomicsDNASANGER SEQUENCING




10Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPE
HLA-DRB3GENE WITH PROTEIN PRODUCT2NOT DONEDRB3*ACME GenomicsDNASANGER SEQUENCING




11Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEDRB4*01:FVUUHLA-DRB4GENE WITH PROTEIN PRODUCT1

ACME GenomicsDNASANGER SEQUENCING




12Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPE
HLA-DRB4GENE WITH PROTEIN PRODUCT2NOT DONEDRB4*ACME GenomicsDNASANGER SEQUENCING




13Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPE
HLA-DRB5GENE WITH PROTEIN PRODUCT1NOT DONEDRB5*ACME GenomicsDNASANGER SEQUENCING




14Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPE
HLA-DRB5GENE WITH PROTEIN PRODUCT2NOT DONEDRB5*ACME GenomicsDNASANGER SEQUENCING




15Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEDQB1*02:ACBXNHLA-DQB1GENE WITH PROTEIN PRODUCT1

ACME GenomicsDNASANGER SEQUENCING




16Study-123GFS123-0011HGA4567VARPROFVariant ProfileALLELE TYPEDQB1*05:ACEDBHLA-DQB1GENE WITH PROTEIN PRODUCT2

ACME GenomicsDNASANGER SEQUENCING




...