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This is an example of an EX dataset for selected animals from a nonclinical inhalation study in rats. Subjects were randomized to 1 of 3 treatment groups

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showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-661

with the test article at dose levels of 0.7, 2.1, and 7.1 mg/kg/day and 1 control group receiving vehicle. The study included 13 weeks of treatment. However, due to severe clinical signs, the dose level for group 4 animals was reduced from 7.1 to 5 during week 6. The other groups remained on the same treatment throughout the study. The animals were placed in inhalation chambers each day for 60 minutes over the 13 weeks period. Prior to first dose and during the study exposure levels were measured by placing a filter for a given time or a set amount of air passing in a port hole in the inhalation chamber. However, the EXDOSE  in this inhalation study contain the planned dose level.

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showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-222

Jira
showSummary false server Issue Tracker (JIRA) serverId 85506ce4-3cb3-3d91-85ee-f633aaaf4a45 key TOBA-221

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