...
This example shows findings from an assessment of genomic variations in human leukocyte antigens (HLA) with the purpose of determining genotyping of
Genotyping of the human leucocyte antigen (HLA) is indispensable for transplantation of hematopoietic stem cells or organs [1–3] and for the management of other diseases involving immune reactions [4].
how variations in those genes affect drug absorption, distribution, metabolism, and excretion (ADME).
The method used to summarize nucleotide variation is represented in variable GFANMETH where appropriate. Identifying information for the genomic panel is represented in SPDEVID. Additional information about the genomic panel may be represented in the Medical Device Domains (e.g., DI domain) as needed.
This example shows findings from an assessment of the unique pattern of sequence variation of one to many loci associated
<> with the purpose of determining <>.
An assessment of the unique pattern of sequence variation of one to many loci associated with a normal or abnormal biological process.
Human leukocyte antigen (HLA) typing
...
| Dataset wrap |
|---|
|
| Dataset2 |
|---|
| Study Identifier | Domain Abbreviation | Unique Subject Identifier | Sponsor Device Identifier | Non-Host Organism Identifier | Sequence Number | Group ID | Reference ID | Sponsor-Defined Identifier | Link ID | Link Group ID | Short Name of Genomic Measurement | Name of Genomic Measurement | Measurement, Test, or Examination Detail | Result or Finding in Original Units | Genomic Symbol | Genomic Symbol Type | Copy Identifier | Completion Status | Reason Test Not Done | External File Path | Laboratory/Vendor Name | Specimen Material Type | Method of Test or Examination | Run ID | Analysis Method | Baseline Flag | Derived Flag | Lower Limit of Quantitation | Repetition Number | Visit Number | Visit Name | Planned Study Day of Visit | Date/Time of Specimen Collection | Study Day of Specimen Collection | Planned Time Point Name | Planned Time Point Number | Planned Elapsed Time from Time Point Ref | Time Point Reference | Date/Time of Reference Time Point | | STUDYID | DOMAIN | USUBJID | SPDEVID | NHOID | GFSEQ | GFGRPID | GFREFID | GFSPID | GFLNKID | GFLNKGRP | GFTESTCD | GFTEST | GFTSTDTL | GFORRES | GFSYM | GFSYMTYP | GFCOPYID | GFSTAT | GFREASND | GFXFN | GFNAM | GFSPEC | GFMETHOD | GFRUNID | GFANMETH | GFBLFL | GFDRVFL | GFLLOQ | GFREPNUM | VISITNUM | VISIT | VISITDY | GFDTC | GFDY | GFTPT | GFTPTNUM | GFELTM | GFTPTREF | GFRFTDTC | | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567An assessment of the unique pattern of sequence variation of one to many loci associated with a normal or abnormal biological process. |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | A*02:TSXZ | HLA-A | GENE WITH PROTEIN PRODUCT | 1 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
| -1 | SCREENING | -1 | 9/16/2023 | -2 |
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | A*03:ABSAX | HLA-A | GENE WITH PROTEIN PRODUCT | 2 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | B*18:TXYF | HLA-B | GENE WITH PROTEIN PRODUCT | 1 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | B*38:01 | HLA-B | GENE WITH PROTEIN PRODUCT | 2 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | C*07:AAEPN | HLA-C | GENE WITH PROTEIN PRODUCT | 1 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | C*12:AAGWE | HLA-C | GENE WITH PROTEIN PRODUCT | 2 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | DRB1*07:ACEUA | HLA-DRB1 | GENE WITH PROTEIN PRODUCT | 1 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | DRB1*14:ABZZV | HLA-DRB1 | GENE WITH PROTEIN PRODUCT | 2 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | DRB3*01:XX | HLA-DRB3 | GENE WITH PROTEIN PRODUCT | 1 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | DRB3* | HLA-DRB3 | GENE WITH PROTEIN PRODUCT | 2 | NOT DONE | DRB3* |
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | DRB4*01:FVUU | HLA-DRB4 | GENE WITH PROTEIN PRODUCT | 1 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE |
| HLA-DRB4 | GENE WITH PROTEIN PRODUCT | 2 | NOT DONE | DRB4* |
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE |
| HLA-DRB5 | GENE WITH PROTEIN PRODUCT | 1 | NOT DONE | DRB5* |
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE |
| HLA-DRB5 | GENE WITH PROTEIN PRODUCT | 2 | NOT DONE | DRB5* |
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | DQB1*02:ACBXN | HLA-DQB1 | GENE WITH PROTEIN PRODUCT | 1 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| | Study-123 | GF | S123-001 |
|
| 1 |
| HGA4567 |
|
|
| VARPROF | Variant Profile | ALLELE TYPE | DQB1*05:ACEDB | HLA-DQB1 | GENE WITH PROTEIN PRODUCT | 2 |
|
|
| ACME Genomics | DNA | SANGER SEQUENCING |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
...