Feature Tracking- make is generic (specify the software program used - Medis/Circle/HeartIT as example, add more)See questions highlighted in red/orange.
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- Is row 4 to delineate between 2D/3D/4D strain analysis LV chamber views? no
- Question for Jon Neville - does ANMETH fit for the place to put the chamber view ofr the MR visualization? - not the right analysis method. The analysis method is related to the intrinsic algorithm performed by the MRI/CMR machine. It is important to know what method was used. These are types of "Feature Tracking".
- Would it be better to show one segment across the different dimensional chamber views at 2 or 3 timepoints? 1, 2, 5 yr point - could do one with change and one without change. Whenever do an MRI - do this; all data can allow feature tracking strain
- Is there a best terminology to use for the dimensions? check CT, 2D, 3D, 4D OR two-dimensional, three-dimensional, four-dimensional (2D is peak radial strain; 3D is peak circumferential strain, 4D is peak longitudinal strain..... is "peak" assumed or does that need to be there?)- not out clinically, more experimentally.
- What test is used to measure fibrosis - is it LGE or strain? May use strain if you think may see... LGE is the answer. Strain is a marker of actual function. It worsens before the LVEF
- (normal - -18 to 20) - -9 is poor
- The LV Global is the average of base/mid/apex circumferential readings/values.
- Longitudinal strain normal is -18%
- LV Global Longitudinal strain is the average of of LV 4, 3, 2 chamber readings/values
-20 is a good result, -10 is a poor result. Could show change over time with first assessment normal, one example could have poor 1 year follow-up and the other can have stable cardiomyopathy disease. Or could just do this. |
Circumferential and Longitudinal Strain are CMR measurement parameters used to evaluate progression of cardiac dysfunction.
SME add relatsionship to DMD
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| Rows 1-3: | Show circumferential strain using the CMR Brand Type (CMRBRANDTYP) Feature tracking analysis for the left ventricular base, mid, and apex regions (CVLOC). | | Row 4: | Shows the left ventricular global circumferential strain (CVLOC=LV Global) and (CVTEST=CIRCUMFERENTIAL STRAIN). | | Row 5: | Shows the circumferential strain for the LV Basal Inferoseptal segment (CVLOC= LEFT VENTRICULAR BASAL INFEROSEPTAL SEGMENT) |
.Rows 5-6: | Show circumferential strain with a 4 dimensional chamber view of the left ventricular basal inferoseptal segment and the left ventricular mid inferoseptal segment| . | | Rows 6-8: | Show the longitudinal strain for 4 chamber, 3 chamber, and 2 chamber of the left ventricle. | | Row 9: | Shows the left ventricular global longitudinal strain (CVLOC=LV Global) and (CVTEST=LONGITUDINAL STRAIN). | | Row 10: | Shows longitudinal strain for the left ventricular 4 chamber basal inferoseptal segment. - check this? was it left over or is correct? |
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Row | STUDYID | DOMAIN | USUBJID | CVSEQ | CVTESTCD | CVTEST | CVORRES | CVORRESU | CVSTRESC | CVSTRESN | CVSTRESU | CVLOC | CVMETHOD | CVANMETH | CVLOBFXL | VISITNUM | VISIT | CVDTC |
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| 1 | DMD-CLS | CV | 401 | 1 | CFSTRAIN | CIRCUMFERENTIAL STRAIN | | % | | -9 | % | HEART, LEFT VENTRICLE, BASE OR LEFT VENTRICULAR BASE
CURRENT CT HAS, HEART, RIGHT VENTRICLE, BASE AND HEART, RIGHT VENTRICLE, MID-LEVEL
***IT MAY BE A DIFFERENT USE CASE. | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature Tracking |
| 1 | SCREENING | 2023-09-01 | | 2 | DMD-CLS | CV | 401 | 2 | CFSTRAIN | CIRCUMFERENTIAL STRAIN | | % | | -12 | % | LEFT VENTRICULAR MID | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | SCREENING | 2023-09-01 | | 3 | DMD-CLS | CV | 401 | 3 | CFSTRAIN | CIRCUMFERENTIAL STRAIN | | % | | -10 | % | LEFT VENTRICULAR APEX | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | SCREENING | 2023-09-01 | | 4 | DMD-CLS | CV | 401 | 4 | CFSTRAIN | CIRCUMFERENTIAL STRAIN | | % | | -10% |
| LEFT VENTRICULAR GLOBAL | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | SCREENING | 2023-09-01 | | 5 | DMD-CLS | CV | 401 | 5 | CFSTRAIN | CIRCUMFERENTIAL STRAIN | | % | | -12 | % | LEFT VENTRICULAR BASAL INFEROSEPTAL SEGMENT | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | SCREENING | 2023-09-01 | | 6 | DMD-CLS | CV | 401 | 6 | LNGSTRAIN | LONGITUDINAL STRAIN | | % | | -18 | % | HEARTLEFT VENTRICLE, 4 CHAMBER | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature Tracking |
| 1 | SCREENING | 2023-09-01 | | 7 | DMD-CLS | CV | 401 | 7 | LNGSTRAIN | LONGITUDINAL STRAIN | | % | | -20 | % | HEART. LEFT VENTRICLE, 3 CHAMBER | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | SCREENING | 2023-09-01 | | 8 | DMD-CLS | CV | 401 | 8 | LNGSTRAIN | LONGITUDINAL STRAIN | | % | | -15 | % | HEART. LEFT VENTRICLE, 2 CHAMBER | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | SCREENING | 2023-09-01 | | 9 | DMD-CLS | CV | 401 | 9 | LNGSTRAIN | LONGITUDINAL STRAIN | | % | | -18 | % | LEFT VENTRICULAR GLOBAL | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | SCREENING | 2023-09-01 | | 10 | DMD-CLS | CV | 401 | 10 | LNGSTRAIN | LONGITUDINAL STRAIN | | % | | -14 | % | LEFT VENTRICULAR 4 CHAMBER BASAL INFEROSEPTAL SEGMENT | CARDIAC MAGNETIC RESONANCE IMAGING | CMRBRANDTYP Feature tracking |
| 1 | SCREENING | 2023-09-01 |
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