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- Is row 4 to delineate between 2D/3D/4D strain analysis LV chamber views?
- Question for Jon Neville - does ANMETH fit for the place to put the chamber view ofr the MR visualization?
- Would it be better to show one segment across the different dimensional chamber views at 2 or 3 timepoints? 1, 2, 5 yr point - could do one with change and one without change. Whenever do an MRI - do this; all data can allow feature tracking strain
- Is there a best terminology to use for the dimensions? check CT, 2D, 3D, 4D OR two-dimensional, three-dimensional, four-dimensional (2D is peak radial strain; 3D is peak circumferential strain, 4D is peak longitudinal strain..... is "peak" assumed or does that need to be there?)- not out clinically, more experimentally.
- What test is used to measure fibrosis - is it LGE or strain? May use strain if you think may see... LGE is the answer. Strain is a marker of actual function. It worsens before the LVEF
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-20 is a good result, -10 is a poor result. Could show change over time with first assessment normal, one example could have poor 1 year follow-up and the other can have stable cardiomyopathy disease. Or could just do this.
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Rows 1-3: | Show circumferential strain with a 3 dimensional chamber view (CVANMETH) of the left ventricular basal anterior segment, left ventricular basal anteroseptal segment, and left ventricular basal inferoseptal segment (CVLOC). | Row 4: | ? - delete? If yes, shall we delete the 4D in the location of rows 5 & 6? | Rows 5-6: | Show circumferential strain with a 4 dimensional chamber view of the left ventricular basal inferoseptal segment and the left ventricular mid inferoseptal segment. |
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Row | STUDYID | DOMAIN | USUBJID | CVSEQ | CVTESTCD | CVTEST | CVORRES | CVORRESU | CVSTRESC | CVSTRESN | CVSTRESU | CVLOC | CVMETHOD | CVANMETH | CVLOBFXL | VISITNUM | VISIT | CVDTC |
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1 | DMD-CLS | CV | 401 | 1 | CFSTRAIN | CIRCUMFERENTIAL STRAIN | -20 (normal - -18 to 20) -9 | % | | -9 | %LEFT | VENTRICULAR BASAL ANTERIOR SEGMENTLV BASE | CARDIAC MAGNETIC RESONANCE IMAGING | 3D -3 chamber viewFeature Tracking- make is generic (specify the software program used - Medis/Circle/HeartIT as example, add more) |
| 1 | SCREENING | 2023-09-01 | 2 | DMD-CLS | CV | 401 | 2 | CFSTRAIN | CIRCUMFERENTIAL STRAIN | | % | | -12 | %LEFT | VENTRICULAR BASAL ANTEROSEPTAL SEGMENTLV MID | CARDIAC MAGNETIC RESONANCE IMAGING | 3D - 30chamber viewMedis feature tracking |
| 1 | SCREENING | 2023-09-01 |
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| LV APEX |
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| LV Global (average of base/mid/apex |
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| 3 | DMD-CLS | CV | 401 | 3 | CFSTRAIN | CIRCUMFERENTIAL STRAIN | | % | | -12 | % | LEFT VENTRICULAR BASAL INFEROSEPTAL SEGMENT | CARDIAC MAGNETIC RESONANCE IMAGING | 3D - 3 chamber viewMedis feature tracking |
| 1 | SCREENING | 2023-09-01 |
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| 4 | DMD-CLS | CV | 401 | 4 | LNGSTRAIN | LONGITUDINAL STRAIN | |
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| | CARDIAC MAGNETIC RESONANCE IMAGING | 4D - 4 chamber viewMedis feature tracking |
| 1 | SCREENING | 2023-09-01 | 5 | DMD-CLS | CV | 401 |
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| LONGITUDINAL STRAIN | |
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| Medis feature tracking |
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| LONGITUDINAL STRAIN | |
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| Medis feature tracking |
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| LONGITUDINAL STRAIN | |
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| Global (average of 4,3,2) |
| Medis feature tracking |
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| 5 | 5 | LNGSTRAIN | LONGITUDINAL STRAIN | | % | | -14 | % | LEFT VENTRICULAR 4 CHAMBER BASAL INFEROSEPTAL SEGMENT | CARDIAC MAGNETIC RESONANCE IMAGING | 4D - 4 chamber view | 1 | SCREENING | 2023-09-01 | 6 | DMD-CLS | CV | 401 | 65 | LNGSTRAIN | LONGITUDINAL STRAIN | | % | | -1314 | % | LEFT VENTRICULAR MID 4 CHAMBER BASAL INFEROSEPTAL SEGMENT | CARDIAC MAGNETIC RESONANCE IMAGING | Medis feature tracking |
| 1 | SCREENING | 2023-09-01 |
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