| Info |
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| title | Questions for the Team |
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- Would there be a baseline at diagnosis of DMD and then a regular follow-up? How often would this occur?
- Yes, but maybe not at diagnosis, sometimes annually or every other year
- What would the anticipated abnormalities be on follow-up CMR?
- Changes in LVF, changes in strain or delayed enhancement, parametric mapping
- Do the CMR images have any cardiac labs done at the same time that would need to be linked (such as a BNP)? If they say yes, I thought we could include text regarding this. I am not sure if it would just be part of the data and not necessarily need to be linked with LNKID.
- NTproBNP, BNP, troponin are the most common
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Measurements such as Cardiac Index (as seen in the example below) and Spirometry are effected by Body Service Area (https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.115.003810). It is important in the DMD population to ensure the height and weight are current for accurate data collection (especially as the participant becomes wheelchair bound). Height and weight are represented in the Vital Signs domain, refer to the SDTMIG v3.4, Section 6.3.13 for more information.
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