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title	Sample from Report Table

The following shows example data for study 123 in a report table. This report includes summary statistics (e.g. Average, Standard Deviation, Coeff. Var.) for each plate and an EC50 value for the entire assay. The grey cells in plate 1 are cells that do not contain the CHO Hamster cellsNHK cells.

Neutral Red Cytotoxicity Assay Results (Relative Absorbance Data)
	Sample ID	Smoke Regime	Replicate Number	Plate Number	Well Number		Relative Assay Plate Absorbance Readings
							Cigarette Smoke Condensate (µg/mL)								SLS (µg/mL)			EC50 (µg/ml)
						0	10	50	75	100	120	140	160	200	110	200	0
	030001	Medium	1	1	1	0.046*	0.046*	0.039*	0.012*	0.030*	0.003*	0.057*	0.032*	0.003*	0.050*	0.044*	0.040*
	030001	Medium	1	1	2	0.048*	107	77.7	65.7	30.2	15.6	9.79	5.41	2.49	8.09	0.791	0.014*
	030001	Medium	1	1	3	0.005*	98.6	77.4	57.7	35.8	8.09	7.36	3.22	0.791	6.38	0.061	0.050*
	030001	Medium	1	1	4	0.049*	94.9	81.5	38.2	31.2	7.60	5.17	3.22	0.791	5.17	0.304	0.017*
	030001	Medium	1	1	5	0.047*	111	78.1	64.5	32.9	8.82	5.90	2.74	1.28	10.3	0.547	0.011*
	030001	Medium	1	1	6	0.032*	96.6	76.2	48.0	26.8	7.84	4.20	2.74	1.52	8.09	4.93	0.022*
	030001	Medium	1	1	7	0.044*	105	77.9	58.2	28.3	8.09	4.68	1.76	0.547	8.57	1.76	0.056*
	030001	Medium	1	1	8	0.056*	0.013*	0.040*	0.008*	0.013*	0.002*	0.029*	0.018*	0.006*	0.016*	0.024*	0.046*
Average							101	78.2	54.5	29.9	9.70	6.17	3.37	1.19	8.94	1.22
Std. Dev.							6	2.9	9.4	3.6	2.95	2.19	1.12	0.72	2.72	1.58
Coeff. Var.							5.8	3.6	17.2	11.9	30.4	35.5	33.1	61.0	30.5	129.9
*media without cells
	030001	Medium	1	2	1		93.4	74.0	56.0	35.1	11.8	8.70	5.10	1.98	5.34	1.02
	030001	Medium	1	2	2		102	75.2	53.3	35.1	11.8	7.74	5.58	3.66	5.34	1.02
	030001	Medium	1	2	3		107	79.0	55.0	26.5	10.1	6.06	3.66	1.74	7.02	0.780
	030001	Medium	1	2	4		104	80.2	55.3	29.8	8.94	3.90	3.66	1.50	6.30	0.780
	030001	Medium	1	2	5		101	75.7	54.1	26.7	4.86	4.38	1.26	1.02	6.30	1.02
	030001	Medium	1	2	6		110	85.7	67.7	26.0	5.34	4.62	3.42	1.50	6.30	0.540
	030001	Medium	1	2	7		104	77.8	64.9	27.7	8.22	3.18	2.46	1.02	6.30	0.780
	030001	Medium	1	2	8		103	71.6	58.9	25.5	9.42	4.14	3.90	1.26	4.38	0.780
Average							103	77.4	58.1	29.0	8.82	5.34	3.63	1.71	5.91	0.840
Std. Dev.							5	4.4	5.3	4.0	2.63	1.97	1.37	0.86	0.83	0.170
Coeff. Var.							4.6	5.6	9.2	13.6	29.8	36.9	37.6	50.0	14.1	20.2
EC50 (µg/ml). Effective concentration at 50% cytotoxicity. (using a specific sigmoidal equation = model).																		123

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Dataset wrap

Jira

showSummary	false
server	Issue Tracker (JIRA)
serverId	85506ce4-3cb3-3d91-85ee-f633aaaf4a45
key	TOBA-279

Rowcaps

Rows 1-12:	Show the test conditions for the set with a short name or SETCD value of ALL. The sponsor chose this value to represent test conditions for the entire assay.
Rows 13-20:	Show the test conditions for the set with a short name or SETCD value of CSC-50b. The sponsor chose this value to represent plate number 1, well number 1, with a concentration of 50µg/mLof Cigarette Smoke Condensate as shown in the report table for study 123.
Row 20:	Shows the value for STRAIN/SUBSTRAIN is NO STRAIN Cell Line, CELLLN, is NOT APPLICABLE because the well is a media only well, having no CHO Hamster NHK cells.
Rows 21-28:	Show the test conditions for the set with a short name or SETCD value of CSC-50. The sponsor chose this value to represent plate number 1, well number 2, with a concentration of 50µg/mLof Cigarette Smoke Condensate as shown in the report table for study 123.
Rows 29-36:	Show the test conditions for the set with a short name or SETCD value of SLS-110. The sponsor chose this value to represent both wells numbered 7 in plate number 1 and 2, with a concentration of 110µg/mLof Sodium Laurel Sulfate as shown in the report table for study 123.

Dataset2

NO STRAINCHOCHO

Row	STUDYID	GNTXAID	DOMAIN	SETCD	SET	TXSEQ	TXPARMCD	TXPARM	TXVAL
1	123	NRU	TX	ALL	ALL_ASSAY	1	TRTDMIN	Treatment Duration Minimum	47.5
2	123	NRU	TX	ALL	ALL_ASSAY	2	TRTDTRG	Treatment Duration Target	48
3	123	NRU	TX	ALL	ALL_ASSAY	3	TRTDMAX	Treatment Duration Maximum	48.5
4	123	NRU	TX	ALL	ALL_ASSAY	4	TRTDU	Treatment Duration Unit	HOURS
5	123	NRU	TX	ALL	ALL_ASSAY	5	INCBTMP	Incubation Temperature	37
6	123	NRU	TX	ALL	ALL_ASSAY	6	INCBTMPU	Incubation Temperature Unit	C
7	123	NRU	TX	ALL	ALL_ASSAY	7	WAVELGTH	Spectrophotometer wavelength in nanometers	540
8	123	NRU	TX	ALL	ALL_ASSAY	8	HUMID	Atmospheric Relative Humidity Percent	90
9	123	NRU	TX	ALL	ALL_ASSAY	9	ATMCO2	Atmospheric CO2 Percent	5
10	123	NRU	TX	ALL	ALL_ASSAY	10	SPDEVID	Sponsor defined device identifier	PUFFMASTER3k
11	123	NRU	TX	ALL	ALL_ASSAY	11	DUREFID	Smoking Regime	Medium Intensity Regimen
12	123	NRU	TX	ALL	ALL_ASSAY	12	SPTOBID	Sponsor defined tobacco identifier	CIG01a
13	123	NRU	TX	CSC-50b	CSC-50-blank	13	PSETCD	Parent Set Code	ALL
14	123	NRU	TX	CSC-50b	CSC-50-blank	14	EXPTYP	Exposure Type	Air Liquid Interface
15	123	NRU	TX	CSC-50b	CSC-50-blank	15	SAMTYP	Sample Type	Whole Smoke Conditioned Media
16	123	NRU	TX	CSC-50b	CSC-50-blank	16	INTRVN	Name of the Intervention Article	Tobacco ProdA
17	123	NRU	TX	CSC-50b	CSC-50-blank	17	ITVTYPE	type of intervention article	PRODUCT
18	123	NRU	TX	CSC-50b	CSC-50-blank	18	ITVCONC	intervention concentration	50
19	123	NRU	TX	CSC-50b	CSC-50-blank	19	ITVCONCU	intervention unit	ug/ml
20	123	NRU	TX	CSC-50b	CSC-50-blank	20	STRAIN	Strain/Substrain	CELLLN	Cell Line	NOT APPLICABLE
21	123	NRU	TX	CSC-50	CSC-50	21	PSETCD	Parent Set Code	ALL
22	123	NRU	TX	CSC-50	CSC-50	22	EXPTYP	Exposure Type	Air Liquid Interface
23	123	NRU	TX	CSC-50	CSC-50	23	SAMTYP	Sample Type	Whole Smoke Conditioned Media
24	123	NRU	TX	CSC-50	CSC-50	24	INTRVN	Name of the Intervention Article	Tobacco ProdA
25	123	NRU	TX	CSC-50	CSC-50	25	ITVTYPE	type of intervention article	PRODUCT
26	123	NRU	TX	CSC-50	CSC-50	26	ITVCONC	intervention concentration	50
27	123	NRU	TX	CSC-50	CSC-50	27	ITVCONCU	intervention unit	ug/ml
28	123	NRU	TX	CSC-50	CSC-50	28	STRAIN	Strain/Substrain	CELLLN	Cell Line	NHK
29	123	NRU	TX	SLS-110	SLS-110	29	PSETCD	Parent Set Code	ALL
30	123	NRU	TX	SLS-110	SLS-110	30	EXPTYP	Exposure Type	Air Liquid Interface
31	123	NRU	TX	SLS-110	SLS-110	31	SAMTYP	Sample Type	Liquid
32	123	NRU	TX	SLS-110	SLS-110	32	INTRVN	Name of the Intervention Article	Sodium Laurel Sulfate
33	123	NRU	TX	SLS-110	SLS-110	33	ITVTYPE	type of intervention article	POSITIVE CONTROL
34	123	NRU	TX	SLS-110	SLS-110	34	ITVCONC	intervention concentration	200
35	123	NRU	TX	SLS-110	SLS-110	35	ITVCONCU	intervention unit	ug/ml
36	123	NRU	TX	SLS-110	SLS-110	36	STRAIN	Strain/Substrain	CELLLN	Cell Line	NHK

Dataset wrap

Name	relref

Jira

showSummary	false
server	Issue Tracker (JIRA)
serverId	85506ce4-3cb3-3d91-85ee-f633aaaf4a45
key	TOBA-280

Rowcaps

Row 1:	Shows the REFID of 123NRU that indicates the entire assay.
Rows 2, 5, 8, 9:	Show the REFIDs at the second level, all within the parent assay of 123NRU (REFID values of 1-3b, 1-3, 1-10, 2-10).
Rows 3-4, 6-7, 10-11:	Show REFID values that the sponsor chose, in this case, to represent the plate number (1 or 2), column (1 - 10), and row (A-G) of the 96-well plate.
Rows 3-4:	Show the REFIDs 1-3-A and 1-3-H that indicate two experimental units within the parent Trial Set of 1-3b.
Rows 6-7:	Show the REFIDs 1-3-B and 1-3-C that indicate two experimental units within the parent Trial Set of 1-3.
Row 10:	Shows the REFID of 1-10-G that indicates the experimental unit within the parent Trial Set of 1-10.
Row 11:	Shows the REFID of 2-10-G that indicates the experimental unit within the parent Trial Set of 2-10.

Dataset2

tableid	relref

Row	STUDYID	GNTXAID	SETCD	REFID	PARENT	LEVEL	LVLDESC
1	123	NRU	ALL	123NRU		1	ASSAY
2	123	NRU	CSC-50b	1-3b	123NRU	2	TRIAL SET
3	123	NRU	CSC-50b	1-3-A	1-3b	3	EXPERIMENTAL UNIT
4	123	NRU	CSC-50b	1-3-H	1-3b	3	EXPERIMENTAL UNIT
5	123	NRU	CSC-50	1-3	123NRU	2	TRIAL SET
6	123	NRU	CSC-50	1-3-B	1-3	3	EXPERIMENTAL UNIT
7	123	NRU	CSC-50	1-3-C	1-3	3	EXPERIMENTAL UNIT
8	123	NRU	SLS-110	1-10	123NRU	2	TRIAL SET
9	123	NRU	SLS-110	2-10	123NRU	2	TRIAL SET
10	123	NRU	SLS-110	1-10-G	1-10	3	EXPERIMENTAL UNIT
11	123	NRU	SLS-110	2-10-G	2-10	3	EXPERIMENTAL UNIT

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