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In tobacco studies, biomarkers to assess exposure or potential harm are both of interest. Biomarkers of exposure are tobacco constituents or their metabolites in a biological fluid or tissue, hair, nails, or exhaled breath.

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They are not measurements of how these constituents interact with the body process/functions. Biomarkers of harm or potential harm are measurements of an effect from exposure. These biomarkers could be indicative of exposure to tobacco products or could be related to diet or environmental exposure. 

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