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This example shows measurements on 2 animals at 3 time points (baseline, 120 minutes, 240 minutes) relative to the administration of the third dose level of a Latin square design (with CVTPTREF as "Dose 3"). |
At each time point, several measurements were assessed (arterial diastolic pressure, arterial heart rate, arterial mean blood pressure). Each measurement summarizes data collected for a planned evaluation interval of 60 minutes that ended at time 0 min, 120 min, and 240 min after the dose. Subject 1003 received the third dose level on day 15 of the study and subject 1008 received this dose level on day 1. The method "Intravascular" is used for measurements taken directly from the vasculature.
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Dataset2 |
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Row | STUDYID | DOMAIN | USUBJID | CVSEQ | CVTESTCD | CVTEST | CVPOS | CVORRES | CVORRESU | CVSTRESC | CVSTRESN | CVSTRESU | CVMETHOD | CVCSTATE | CVBLFL | CVDTC | CVDY | CVNOMDY | CVTPT | CVTPTNUM | CVELTM | CVTPTREF | CVRFTDTC | CVSTINT | CVENINT |
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1 | AA222 | CV | 1003 | 1 | DIABP | Diastolic Blood Pressure | UNCONSTRAINED | 50.94 | mmHg | 50.94 | 50.94 | mmHg | Intravascular | CONSCIOUS | Y | 2006-09-15 | 15 | 15 | 0 min | 0 | PT0M | Dose 3 | 2006-09-15T10:30 | -PT60M | PT0M | 2 | AA222 | CV | 1003 | 2 | DIABP | Diastolic Blood Pressure | UNCONSTRAINED | 50.68 | mmHg | 50.68 | 50.68 | mmHg | Intravascular | CONSCIOUS |
| 2006-09-15 | 15 | 15 | 120 min | 120 | PT120M | Dose 3 | 2006-09-15T10:30 | PT60M | PT120M | 3 | AA222 | CV | 1003 | 3 | DIABP | Diastolic Blood Pressure | UNCONSTRAINED | 49.37 | mmHg | 49.37 | 49.37 | mmHg | Intravascular | CONSCIOUS |
| 2006-09-15 | 15 | 15 | 240 min | 240 | PT240M | Dose 3 | 2006-09-15T10:30 | PT180M | PT240M | 4 | AA222 | CV | 1003 | 4 | HR | Heart Rate | UNCONSTRAINED | 139.2 | beats/min | 139.2 | 139.2 | beats/min | Intravascular | CONSCIOUS | Y | 2006-09-15 | 15 | 15 | 0 min | 0 | PT0M | Dose 3 | 2006-09-15T10:30 | -PT60M | PT0M | 5 | AA222 | CV | 1003 | 5 | HR | Heart Rate | UNCONSTRAINED | 128.3 | beats/min | 128.3 | 128.3 | beats/min | Intravascular | CONSCIOUS |
| 2006-09-15 | 15 | 15 | 120 min | 120 | PT120M | Dose 3 | 2006-09-15T10:30 | PT60M | PT120M | 6 | AA222 | CV | 1003 | 6 | HR | Heart Rate | UNCONSTRAINED | 118.4 | beats/min | 118.4 | 118.4 | beats/min | Intravascular | CONSCIOUS |
| 2006-09-15 | 15 | 15 | 240 min | 240 | PT240M | Dose 3 | 2006-09-15T10:30 | PT180M | PT240M | 7 | AA222 | CV | 1003 | 7 | MAP | Mean Arterial Pressure | UNCONSTRAINED | 66.96 | mmHg | 66.96 | 66.96 | mmHg | Intravascular | CONSCIOUS | Y | 2006-09-15 | 15 | 15 | 0 min | 0 | PT0M | Dose 3 | 2006-09-15T10:30 | -PT60M | PT0M | 8 | AA222 | CV | 1003 | 8 | MAP | Mean Arterial Pressure | UNCONSTRAINED | 66.66 | mmHg | 66.66 | 66.66 | mmHg | Intravascular | CONSCIOUS |
| 2006-09-15 | 15 | 15 | 120 min | 120 | PT120M | Dose 3 | 2006-09-15T10:30 | PT60M | PT120M | 9 | AA222 | CV | 1003 | 9 | MAP | Mean Arterial Pressure | UNCONSTRAINED | 65.99 | mmHg | 65.99 | 65.99 | mmHg | Intravascular | CONSCIOUS |
| 2006-09-15 | 15 | 15 | 240 min | 240 | PT240M | Dose 3 | 2006-09-15T10:30 | PT180M | PT240M | 10 | AA1111 | CV | 1008 | 10 | DIABP | Diastolic Blood Pressure | UNCONSTRAINED | 34.11 | mmHg | 34.11 | 34.11 | mmHg | Intravascular | CONSCIOUS | Y | 2006-09-01 | 1 | 1 | 0 min | 0 | PT0M | Dose 3 | 2006-09-01T10:30 | -PT60M | PT0M | 11 | AA1111 | CV | 1008 | 11 | DIABP | Diastolic Blood Pressure | UNCONSTRAINED | 28.63 | mmHg | 28.63 | 28.63 | mmHg | Intravascular | CONSCIOUS |
| 2006-09-01 | 1 | 1 | 120 min | 120 | PT120M | Dose 3 | 2006-09-01T10:30 | PT60M | PT120M | 12 | AA1111 | CV | 1008 | 12 | DIABP | Diastolic Blood Pressure | UNCONSTRAINED | 28.96 | mmHg | 28.96 | 28.96 | mmHg | Intravascular | CONSCIOUS |
| 2006-09-01 | 1 | 1 | 240 min | 240 | PT240M | Dose 3 | 2006-09-01T10:30 | PT180M | PT240M | 13 | AA1111 | CV | 1008 | 13 | HR | Heart Rate | UNCONSTRAINED | 186.1 | beats/min | 186.1 | 186.1 | beats/min | Intravascular | CONSCIOUS | Y | 2006-09-01 | 1 | 1 | 0 min | 0 | PT0M | Dose 3 | 2006-09-01T10:30 | -PT60M | PT0M | 14 | AA1111 | CV | 1008 | 14 | HR | Heart Rate | UNCONSTRAINED | 168.3 | beats/min | 168.3 | 168.3 | beats/min | Intravascular | CONSCIOUS |
| 2006-09-01 | 1 | 1 | 120 min | 120 | PT120M | Dose 3 | 2006-09-01T10:30 | PT60M | PT120M | 15 | AA1111 | CV | 1008 | 15 | HR | Heart Rate | UNCONSTRAINED | 150.8 | beats/min | 150.8 | 150.8 | beats/min | Intravascular | CONSCIOUS |
| 2006-09-01 | 1 | 1 | 240 min | 240 | PT240M | Dose 3 | 2006-09-01T10:30 | PT180M | PT240M | 16 | AA1111 | CV | 1008 | 16 | MAP | Mean Arterial Pressure | UNCONSTRAINED | 53.48 | mmHg | 53.48 | 53.48 | mmHg | Intravascular | CONSCIOUS | Y | 2006-09-01 | 1 | 1 | 0 min | 0 | PT0M | Dose 3 | 2006-09-01T10:30 | -PT60M | PT0M | 17 | AA1111 | CV | 1008 | 17 | MAP | Mean Arterial Pressure | UNCONSTRAINED | 47.67 | mmHg | 47.67 | 47.67 | mmHg | Intravascular | CONSCIOUS |
| 2006-09-01 | 1 | 1 | 120 min | 120 | PT120M | Dose 3 | 2006-09-01T10:30 | PT60M | PT120M | 18 | AA1111 | CV | 1008 | 18 | MAP | Mean Arterial Pressure | UNCONSTRAINED | 46.48 | mmHg | 46.48 | 46.48 | mmHg | Intravascular | CONSCIOUS |
| 2006-09-01 | 1 | 1 | 240 min | 240 | PT240M | Dose 3 | 2006-09-01T10:30 | PT180M | PT240M | |
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