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title	tx.xpt (trial sets)

How do we handle "toxic, no revertant colonies"? (LAK will add 6 records with GTSTAT = NOT DONE, GTREASND = "TOO MUCH CYTOTOXICITY,"
Condition of background bacterial lawn? Slight thinning, Very thin? - refer to SEND team's marked-up table.
- new Test code of Cytotoxicity with GTORRES = S, V (controlled terms)
- Each plate we would have one result record for Revertent count and another for the lawn evaluation (NORMAL, SLIGHT THINNING, VERY THIN)
When "-" in Mean, Std Dev, Fold Inc - refer to SEND team's marked-up table (GTSTAT = NOT DONE; variety of REASND)

Below the SETS shown in the TX table are rows A, F, I, and R (probably don't need R)

Row	STUDYID	ASSAYID	DOMAIN	SETCD	SET (what sponsor calls it)	TXPARMCD	TXPARM	TXVAL
1	8325064	Ames	TX	SetA	A-TA98-C0	SPECIES	Species	Salmonella typhimurium
2	8325064	Ames	TX	SetA	A-TA98-C0	STRAIN	Strain/Substrain	TA98
3	8325064	Ames	TX	SetA (Row 1)	A-TA98-C0	METACT	Metabolic Activation
4						METACTFL	Y/N presence of metabolic activation	N
5	8325064	Ames	TX	SetA		TRTDMIN	Treatment Duration Minimum	71.5
6	8325064	Ames	TX	SetA		TRTDTRG	Treatment Duration Target	72
7	8325064	Ames	TX	SetA		TRTDMAX	Treatment Duration Maximum	72.5
8	8325064	Ames	TX	SetA		TRTDU	Treatment Duration Unit	HOURS
9	8325064	Ames	TX	SetA		INCBTMP	Incubation Temperature	37
10	8325064	Ames	TX	SetA		INCBTMPU	Incubation Temperature Unit	C
11	8325064	Ames	TX	SetA		HUMID	Atmospheric Relative Humidity Percent	50
12	8325064	Ames	TX	SetA		ATMCO2	Atmospheric CO2 Percent	5
13	8325064	Ames	TX	SetA		SPTOBID	Sponsor defined tobacco identifier	CIG01a
14	8325064	Ames	TX	SetA		EXPTYP	Exposure Type (See TIG NC workstream minutes 30-Jan here: Nonclinical)	Submerged
15	8325064	Ames	TX	SetA		SAMTYP	Sample Type	Total Particulate Matter in PBS
16	8325064	Ames	TX	SetA		INTRVN	name of the intervention article	TA1
17	8325064	Ames	TX	SetA		ITVTYPE	type of intervention article	Vehicle Control
18	8325064	Ames	TX	SetA		ITVCONC	Concentration of intervention article	0
19	8325064	Ames	TX	SetA		ITVCONCU	Concentration Unit	ug/plate
20	8325064	Ames	TX	SetA		TRTV	Treatment Vehicle	DMSO
21	8325064	Ames	TX	SetA		SPDEVID	Sponsor defined device identifier	PUFFMASTER3K
...						DUREFID	Smoke Regimen	Medium Intensity Regimen
	8325064	Ames	TX	SetF (row 6)		METACT	Metabolic Activation (should there be two parms? Presence, type)?	None
	8325064	Ames	TX	SetF		TRTDRTRG	Treatment Duration target. (how do we show 3-6 hour range? start/end, target and tolerance?, one text field not-analyzable)
	8325064	Ames	TX	SetF		TRTDRTOL	Treatment Duration Tolerance
	8325064	Ames	TX	SetF		TRTDURU	Treatment Duration Unit (this is for both TRTDURT, TRTDURTOL)
	8325064	Ames	TX	SetF		INTRVN	name of the intervention article (Tobacco ProdA, Bleomycin or Cyclophosphamid A)	TA1
	8325064	Ames	TX	SetF		ITVTYPE	type of intervention article choices of values: product; negative control; positive control	Product
	8325064	Ames	TX	SetF		ITVCONC	Concentration of intervention article	500
	8325064	Ames	TX	SetF		ITVCONCU	Concentration Unit	ug/plate
	8325064	Ames	TX	SetF		STRAIN	Strain/Substrain	TA98
	8325064	Ames	TX	SetF		REGIME	Smoking Regime	ISO Regime
...
	8325064	Ames	TX	SetISetG (row 9)7) do G not I!!!		METACT	Metabolic Activation (should there be two parms? Presence, type)?	None
	8325064	Ames	TX	SetI (row 9)		TRTDRTRG	Treatment Duration target. (how do we show 3-6 hour range? start/end, target and tolerance?, one text field not-analyzable)
	8325064	Ames	TX	SetI		TRTDRTOL	Treatment Duration Tolerance
	8325064	Ames	TX	SetI		TRTDURU	Treatment Duration Unit (this is for both TRTDURT, TRTDURTOL)
	8325064	Ames	TX	SetI		INTRVN	name of the intervention article (Tobacco ProdA, Bleomycin or Cyclophosphamid A)	2-Nitrofluorine
	8325064	Ames	TX	SetI		ITVTYPE	type of intervention article choices of values: product; negative control; positive control	Positive Control
	8325064	Ames	TX	SetI		ITVCONC	Concentration of intervention article	5
	8325064	Ames	TX	SetI		ITVCONCU	Concentration Unit	ug/plate
	8325064	Ames	TX	SetI		REGIME	Smoking Regime	ISO
...
	8325064	Ames	TX	SetR (Row 18)		METACT	Metabolic Activation (should there be two parms? Presence, type)?	None
	8325064	Ames	TX	SetR		TRTDRTRG	Treatment Duration target. (how do we show 3-6 hour range? start/end, target and tolerance?, one text field not-analyzable)
	8325064	Ames	TX	SetR		TRTDRTOL	Treatment Duration Tolerance
	8325064	Ames	TX	SetR		TRTDURU	Treatment Duration Unit (this is for both TRTDURT, TRTDURTOL)
	8325064	Ames	TX	SetR		INTRVN	name of the intervention article (Tobacco ProdA, Bleomycin or Cyclophosphamid A)	4-Nitroquinoline-1-oxide
	8325064	Ames	TX	SetR		ITVTYPE	type of intervention article choices of values: product; negative control; positive control	Positive Control
	8325064	Ames	TX	SetR		ITVCONC	Concentration of intervention article	2
	8325064	Ames	TX	SetR		ITVCONCU	Concentration Unit	ug/plate
	8325064	Ames	TX	SetR		STRAIN	Strain/Substrain	TA98
	8325064	Ames	TX	SetR		REGIME	Smoking Regime	ISO

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Key

SET (what sponsor calls it)