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A domain is defined as a collection of logically related observations with a common topic. The logic of the relationship may pertain to the scientific subject matter of the data or to its role in the trial. SEND

Datasets and Domains - SENDIG v3.1.1 - Wiki (cdisc.org) 

A domain is defined as a collection of logically related observations with a common topic. The logic of the relationship may pertain to the scientific subject matter of the data or to its role in the study. 

What or who is a subject

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