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Smoking/Vaping topography is how the smoker smokes/vapes a tobacco product. Measures of vaping/smoking behavior is critical to understand exposures to biomarkers of nicotine exposure and toxins. There are topography devices that are used to measure cigarette puffing behavior, these devices may also be used evaluate electronic cigarette use. There are also calibrated laboratory-based smoking puff analyzer devices that are combined with an analytical smoking machine that generates programmable puffs with high precision. Puff, inhalation and exhalation duration; puff volume; inter puff interval are often measured. Sponsors may find information in a Technical Document has been published on the CORESTA website (Oct 2022): Assessing Product Use Behaviour and Exposure: Definitions and Methods

Puff topography is typically considered data about the subject exposure to the test product. As these data repesent information about study product exposure, the data is represeted in the Exposure (EX) domain. More informaion on the Exposure domain is found here.      

Example

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SDTM Example.Puff Topogaphy
SDTM Example.Puff Topogaphy