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title	tx.xpt (trial sets)

During CT definition/reviews will decide appropriate TXPARM and TXVAL; Treatment duration may be controlled; For now, we just include good example values based on our experience
Assumption: The Trial Sets (TX) domain provides the list of distinct sets of subjects having different experimental factors, treatment factors, inherent characteristics, or distinct sponsor designations as specified in the trial design.
Where is TK6 cell type? is this test system (see below)
- needs to be allowed to vary down to the well level / result level
Check Essential Data list

A1:

A2:

Row	STUDYID	ASSAYID	DOMAIN	SETCD	SET (what sponsor calls it, more meaningful label for Tables)	TXSEQ	TXPARMCD	TXPARM	TXVAL
	123	MNvit	TX	A1 (table 1, row 1, ST exposure with S9)	ST+S9C0	1	METACT	Metabolic Activation (this is the type of activation used)	+S9
	123	MNvit	TX	A1	ST+S9C0	2	METACTFL	Y/N presence of metabolic activation (this indicates that metabolic activation was used)	Y
						3	TRTDMIN	Treatment Duration Min (ask Jon the terminology used)
						4	TRTDTRG	Treatment Duration Target
						5	TRTDMAX	Treatment Duration Max
						6	TRTDU	Treatment Duration Unit
						7	RCVDMIN	Recovery Duration Min
						8	RCVDTRG	Recovery Duration Target
						9	RCVDMAX	Recovery Duration Max
						10	RCVDU	Recovery Duration Unit
						11	INCBTMP	Incubation Temperature
						12	INCBTMPU	Incubation Temperature Unit
						13	MEDIA	Composition of Media
						14	HUMID	Atmospheric HumidityRelative Humidity Percent
						15	ATMCO2	Atmospheric CO2 Percent
							SPTOBID	Sponsor defined tobacco identifier	CIG01a
							SMKEXSYS	Smoke Exposure System	Cambridge filter pad, eluted in DMSO
	123	MNvit	TX	A1	ST+S9C0	6	INTRVN	name of the intervention article can be: Tobacco ProdA, Bleomycin (positive control) or Cyclophosphamid A (positive control)	Tobacco ProdA
	123	MNvit	TX	A1	ST+S9C0	7	ITVTYPE	type of intervention article choices of values: product; negative control; positive control	Negative Control
	123	MNvit	TX	A1	ST+S9C0	8	ITVCONC	Concentration of intervention article	0
	123	MNvit	TX	A1	ST+S9C0	9	ITVCONCU	Concentration Unit	ug/ml
	123	MNvit	TX	A1	ST+S9C0	10	SPDEVID	Sponsor defined device identifier	PUFFMASTER3K
	123	MNvit	TX	A1	ST+S9C0	11	DUREFID	Smoke Regimen	Medium Intensity Regimen
							SMKEXSYS	Smoke Exposure System	Cambridge filter pad, eluted in DMSO
	123	MNvit	TX	A2 (table 1, row 2, ST exposure with S9 at concentration 1250)	ST+S9-1250	1	METACT	Metabolic Activation (should there be two parms? Presence, type)?	+S9
	123	MNvit	TX	A2		2	METACTFL	Y/N presence of metabolic activation (this indicates that metabolic activation was used)	Y
	123	MNvit	TX	A2		3	TRTDRTRG	Treatment Duration target. (how do we show 3-6 hour range? start/end, target and tolerance?, one text field not-analyzable)	3
	123	MNvit	TX	A2		4	TRTDRTOL	Treatment Duration Tolerance
	123	MNvit	TX	A2		5	TRTDURU	Treatment Duration Unit (this is for both TRTDURT, TRTDURTOL)	H
	123	MNvit	TX	A2		6	INTRVN	name of the intervention article	Tobacco ProdA
	123	MNvit	TX	A2		7	ITVTYPE	type of intervention article	Product
	123	MNvit	TX	A2		8	ITVCONC	Concentration of i a	1250
	123	MNvit	TX	A2		9	ITVCONCU	Concentration Unit	ug/ml
	123	MNvit	TX	A2		10	SPDEVID	Sponsor defined device identifier	PUFFMASTER2023
	123	MNvit	TX	A2		11	DUREFID	Smoke Regimen	High Intensity Regimen
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Key

SET (what sponsor calls it, more meaningful label for Tables)