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In this study, subjects were randomized to one of three nicotine dosage levels. At the baseline visit (Week 0), they received an ENDS device that used 0, 8 or 24 mg/ml nicotine liquid. Self-reported daily cigarette consumption was recorded for each day of the study for 4 weeks. The subjects were supplied replacement nicotine cartridges at each weekly visit. The sponsor used an electronic diary application to track when the cartridges were inserted and removed, and the daily number of cigarettes smoked. The subject used their normal brand cigarettes, and these were not supplied by the sponsor, and are not considered a study product. Each cartridge was 8 mL. No other nicotine replacement products were allowed to be used. Multiple cartridges were dispensed at a visit.   

The sponsor represented the cigarettes used in the in the SU domain. The After the first visit, the number of cigarettes smoked for each day of the study after the first visit were represented. If no cigarettes were smoked, Although, "0" records are typically not included, 0 was recorded as the data was collected. Only a few rows are shown.    

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