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The next diagram shows the trial from the viewpoint of blinded participants. To blinded participants in this trial, all arms look alike. They know when a subject is in the screen element or the run-in element, but when a subject is in the treatment epoch, participants know only that the subject is receiving a study drug, not which study drug, and therefore not which element.
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A trial design matrix is a table with a row for each arm in the trial and a column for each epoch in the trial. It is closely related to the retrospective view of the trial, and many users may find it easier to construct a table than to draw a diagram. The cells in the matrix represent the study cells, which are populated with trial elements. In this trial, each study cell contains exactly 1 element.
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