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Open-ended findings modeling: What ANA stain pattern do you observe? (This is the IS Example 10 in the SDTMIG v3.4)
Con: This approach would only allow people to report the positive findings.
LOINC codes:
- https://loinc.org/14722-3/ Presence
- https://loinc.org/29953-7/ Titer
- https://loinc.org/14611-8/ Pattern
| Dataset wrap |
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| Dataset2 |
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Row | STUDYID | DOMAIN | USUBJID | ISSEQ | ISREFID | ISGRPID | ISTESTCD | ISTEST | ISBDAGNT | ISTSTDTL | ISTSTOPO | ISORRES | ISORRESU | ISSTRESC | ISSTRESN | ISSTRESU | ISSPEC | ISMETHOD | VISITNUM | VISIT | ISDTC |
|---|
| 1 | XYZ | IS | XYZ1234 | 1 | 19283746 | 1 | ATAB | Autoantibody | NUCLEAR AUTOANTIGENS |
| SCREEN | POSITIVE |
| POSITIVE |
|
| SERUM | FLUORESCENT IMMUNOASSAY | 1 | SCREENING | 2018-06-20 |
|---|
| 2 | XYZ | IS | XYZ1234 | 2 | 19283746 | 1a | ATAB | Autoantibody | NUCLEAR AUTOANTIGENS |
| QUANTIFY | 1:340 |
| 340 | 340 | titer | SERUM | FLUORESCENT IMMUNOASSAY | 1 | SCREENING | 2018-06-20 |
|---|
| 3 | XYZ | IS | XYZ1234 | 3 | 19283746 | 1a | ATAB | Autoantibody | NUCLEAR AUTOANTIGENS | STAINING PATTERN |
| CYTOPLASMIC,
SPECKLED PATTERN |
| CYTOPLASMIC, SPECKLED PATTERN |
|
| SERUM | FLUORESCENT IMMUNOASSAY | 1 | SCREENING | 2018-06-20 |
|---|
| 4 | XYZ | IS | XYZ1234 | 4 | 19283746 | 1b | ATAB | Autoantibody | NUCLEAR AUTOANTIGENS |
| QUANTIFY | 1:170 |
| 170 | 170 | titer | SERUM | FLUORESCENT IMMUNOASSAY | 1 | SCREENING | 2018-06-20 |
|---|
| 5 | XYZ | IS | XYZ1234 | 5 | 19283746 | 1b | ATAB | Autoantibody | NUCLEAR AUTOANTIGENS | STAINING PATTERN |
| NUCLEAR, NUCLEOLAR PATTERN |
| NUCLEAR, NUCLEOLAR PATTERN |
|
| SERUM | FLUORESCENT IMMUNOASSAY | 1 | SCREENING | 2018-06-20 |
|---|
| 6 | XYZ | IS | XYZ1007 | 1 | 19283746 | 1 | ATAB | Autoantibody | NUCLEAR AUTOANTIGENS |
| SCREEN | NEGATIVE |
| NEGATIVE |
|
| SERUM | FLUORESCENT IMMUNOASSAY | 1 | SCREENING | 2018-06-20 |
|---|
|
|
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Pre-specified findings modeling: Do you observe nuclear centromere/cytoplasmic speckled ANA pattern?
Pro:
- This approach allows the users to report both the specific positive and negative patterns, if interested.
- This is also almost a 1:1 mapping to LOINC codes.
LOINC Codes:
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