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ItemGroupRef references an ItemGroupDef as it occurs within a specific StudyEventDef or ItemGroupDef. The list of ItemGroupRefs identifies the types of item groups that are allowed to occur within this type of studyevent or (nested) itemgroupitem groupThe ItemGroupRefs within a single StudyEventDef or ItemGroupDef must not have duplicate ItemGroupOID or OrderNumber attribute values.

The MethodOID references a MethodDef used to pre-populate prepopulate items.

The OrderNumber attribute provides an ordering on the ItemGroupDefs (within StudyEventDef or ItemGroupDef) for use whenever a list of ItemGroupDefs is presented to a user. Order of execution is preferably defined in a workflow (see Section 3.2.2.1.8, WorkflowDef)   but when used without a workflow, may be used the define the order in which data entry forms are presented in an application UI. 

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