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title	tx.xpt (trial sets)

Assumption: The Trial Sets (TX) domain provides the list of distinct sets of subjects having different experimental factors, treatment factors, inherent characteristics, or distinct ~~sponsor~~ applicant designations as specified in the trial design.
During CT definition/reviews will decide appropriate TXPARM and TXVAL; Treatment duration may be controlled; For now, we just include good example values based on our experience
Where are the details of the smoke regime defined/submitted today? (e.g., puff profile = Bell shaped puffing volumes; Puff Block = 50%, etc.)

Row	STUDYID	ASSAYID	DOMAIN	SETCD	SET (what sponsor calls it)	TXPARMCD	TXPARM	TXVAL	Definitions
1	123	NRU	TX	1-1-A (plate-col-row in the 96-well plate)	CSC-10 (through SLS-200)	PLATENUM. (e.g., 1 or 2)	1	1
2	123	NRU	TX	1-1-A	CSC-10	WELLNUM (e.g., 1-A through 10-H)	Number representing the location of the well in the 96-well plate	1-A
3	123	NRU	TX	1-1-A	CSC-10	INTRVN	name of the intervention article	Cigarette Smoke Condensate
4	123	NRU	TX	1-1-A	CSC-10	ITVTYPE (CT e.g, Product, positive control, negative control)	type of intervention article	PRODUCT
5	123	NRU	TX	1-1-A	CSC-10	ITVCONC	intervention concentration	10
6	123	NRU	TX	1-1-A	CSC-10	ITVCONCU	intervention unit	ug/ml
7	123	NRU	TX	1-1-A	CSC-10	STRAIN	Strain/Substrain	Salmonella enterica enterica
8	123	NRU	TX	1-1-A	CSC-10	REGIME	Smoking Regime	Traditional combustible
9	123	NRU	TX	1-1-A	CSC-10	RUN	Assay run number	1
10	123	NRU	TX	1-1-A	CSC-10	PORT	Port ID	1
11	123	NRU	TX	1-1-A	CSC-10	SMPLID	Sample ID	030001
12	123	NRU	TX	1-1-A	CSC-10	SMKFRC	Smoke Fraction	A
13	123	NRU	TX	1-1-A	CSC-10	REPNUM	Replicate Number	1
1	123	NRU	TX	1-1-B	CSC-10	PLATENUM. (e.g., 1 or 2)	1	1
2	123	NRU	TX	1-1-B	CSC-10	WELLNUM (e.g., 1-A through 10-H)	Number representing the location of the well in the 96-well plate	1-A
3	123	NRU	TX	1-1-B	CSC-10	INTRVN	name of the intervention article	Cigarette Smoke Condensate
4	123	NRU	TX	1-1-B	CSC-10	ITVTYPE (CT e.g, Product, positive control, negative control)	type of intervention article	PRODUCT
5	123	NRU	TX	1-1-B	CSC-10	ITVCONC	intervention concentration	10
6	123	NRU	TX	1-1-B	CSC-10	ITVCONCU	intervention unit	ug/ml
7	123	NRU	TX	1-1-B	CSC-10	STRAIN	Strain/Substrain	Salmonella enterica enterica
8	123	NRU	TX	1-1-B	CSC-10	REGIME	Smoking Regime	Traditional combustible
9	123	NRU	TX	1-1-B	CSC-10	RUN (Test Result, use to analyze for biases, group of replicates over time frame and lab condition)	Assay run number	1	Identified at result level,
10	123	NRU	TX	1-1-B	CSC-10	PORT	Port ID	1
11	123	NRU	TX	1-1-B	CSC-10	SMPLID	Sample ID	030001
12	123	NRU	TX	1-1-B	CSC-10	SMKFRC	Smoke Fraction	A
13	123	NRU	TX	1-1-B	CSC-10	REPNUM (Replicated independent separate samples prepared and run the same vs. duplicates across wells, running the same replicate across many wells)	Replicate Number	1	Trial = Sample preps vs. Replicates = different plates Col/Row = testing of an individual sample multiple times


14	123	NRU	TX	1-1-B	CSC-10	ITVCONC	intervention concentration	10
15	123	NRU	TX	1-1-B	CSC-10	ITVCONCU	intervention unit	ug/ml
...				...
	123	NRU	TX	1-10-H	SLS-10	PLATENUM	Plate number	1
	123	NRU	TX	1-10-H	SLS-10	WELLNUM	Number representing the location of the well in the 96-well plate	10-H
	123	NRU	TX	1-10-H	SLS-10	INTRVN	name of the intervention article	sodium laurel sulfate
	123	NRU	TX	1-10-H	SLS-10	ITVTYPE	type of intervention article	POSITIVE CONTROL
	123	NRU	TX	1-10-H	SLS-10	ITVCONC	intervention concentration	200
	123	NRU	TX	1-10-H	SLS-10	ITVCONCU	intervention unit	ug/ml
...				...
	123	NRU	TX	2-10-H	SLS-10	PLATENUM	Plate number	2
	123	NRU	TX	2-10-H	SLS-10	WELLNUM	Number representing the location of the well in the 96-well plate	10-H
	123	NRU	TX	2-10-H	SLS-10	INTRVN	name of the intervention article	sodium laurel sulfate
	123	NRU	TX	2-10-H	SLS-10	ITVTYPE	type of intervention article	POSITIVE CONTROL
	123	NRU	TX	2-10-H	SLS-10	ITVCONC	intervention concentration	200
	123	NRU	TX	2-10-H	SLS-10	ITVCONCU	intervention unit	ug/ml

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title	gt.xpt (similar to LB)

Row	STUDYID	ASSAYID	DOMAIN	TXSETCD	GTSEQ	GTTESTCD	GTTEST	GTORRES	GTORRESU	GTSTRESC	GTSTRESN	GTSTRESU
1	123	NRU	GT	1-1-A	1	RELABS	Relative Absorbance Reading	100	ug/ml	100	100	ug/ml
2	123	NRU	GT	1-1-B	1	RELABS	Relative Absorbance Reading	107	ug/ml	100	100	ug/ml
3	123	NRU	GT	1-1-C	1	RELABS	Relative Absorbance Reading	98.6	ug/ml	100	100	ug/ml
4	123	NRU	GT	1-1-D	1	RELABS	Relative Absorbance Reading	94.9	ug/ml	100	100	ug/ml
5	123	NRU	GT	1-1-E	1	RELABS	Relative Absorbance Reading	111	ug/ml	111	111	ug/ml
	123	NRU	GT	1-1-F	1	RELABS	Relative Absorbance Reading	96.9	ug/ml	96.9	96.9	ug/ml
	123	NRU	GT	1-1-G	1	RELABS	Relative Absorbance Reading	105	ug/ml	105	105	ug/ml
	123	NRU	GT	1-1-H	1	RELABS	Relative Absorbance Reading	95.2	ug/ml	95.2	95.2	ug/ml
10	123	NRU	GT	1-2-A	1	RELABS	Relative Absorbance Reading	83.0	ug/ml	83.0	83.0	ug/ml
11	123	NRU	GT	1-2-B	1	RELABS	Relative Absorbance Reading	77.7	ug/ml	77.7	77.7	ug/ml
...				...
80	123	NRU	GT	1-10-H	1	RELABS	Relative Absorbance Reading	0.791	ug/ml	0.791	0.791	ug/ml
...				...
160	123	NRU	GT	2-10-H	1	RELABS	Relative Absorbance Reading	0.780	ug/ml	0.780	0.780	ug/ml

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Versions Compared

Old Version 24

New Version 25

Key

SET (what sponsor calls it)

(plate-col-row in the 96-well plate)

(through SLS-200)

PLATENUM. (e.g., 1 or 2)

WELLNUM (e.g., 1-A through 10-H)

(CT e.g, Product, positive control, negative control)

PLATENUM. (e.g., 1 or 2)

WELLNUM (e.g., 1-A through 10-H)

(CT e.g, Product, positive control, negative control)