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The National Cancer Institute (NCI) at the National Institutes of Health (NIH) owns the copyright for the PROis the owner of the PRO-CTCAE V1.0measurement system

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 and has made it exempt from copyright restrictions. Use of the PRO-CTCAE V1.0 is subject to NCI terms of use policy listed on the website. Based on these terms of use, CDISC considers this instrument exempt from copyright restrictions. CDISC has included this supplement in the CDISC inventory of QRS data standards supplements. Hence, CDISC developed QSTESTCD and QSTEST for each item based on the actual text on the measurement system

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