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title	ts.xpt (trial summary, study level parameters)

Assumption: Study can have more than one assay type
Assumption: ASSAYID value of ALL means it applies to all assays in the study
Replaced the ASSAYID values of MNT with MNvit (term used in OECD #487) - is this better? This is not a controlled term so we can use anything but what we use in our IG examples are often used in industry implementations so we should use realistic and best practice values as much as possible.
BLEO & CPA - are positive controls, should this be included/where is this captured? — in results for the record / row?
Where is TK6 cell type? is this test system (see below)

OECD Test No. 487 2016-07-29

Row	STUDYID	ASSAYID	DOMAIN	TSSEQ	TSGRPID	TSPARMCD	TSPARM	TSVAL	TSVALNF
1	123	ALLNRU	TS	1		GLPTYP	Good Laboratory Practice Type	FDA
2	123	ALLNRU	TS	2		GLPTYP	Good Laboratory Practice Type	OECD
3	123	ALLNRU	TS	1		STSTDTC	Study Start Date	2022-05-25
4	123	ALLNRU	TS	1		STITLE	Study Title	Determination of the in vitro genotoxicity potential of 10 tobacco products in both the in vitro Micronucleus Assay and the in vitro Neutral Red Uptake
5	123	ALLNRU	TS	1		SNDIGVER	SEND Implementation Guide Version	TOBACCO IMPLEMENTATION GUIDE VERSION 1.0
6	123	ALLNRU	TS	1		SNDCTVER	SEND Controlled Terminology Version	SEND Terminology 2021-09-30
7	123	ALLNRU	TS	1		SSPONSOR	Sponsor Organization	Example Sponsor Inc.
8	123	ALLNRU	TS	1		SPREFID	Sponsor's Study Reference ID		NOT APPLICABLE
9	123	ALLNRU	TS	1	1	TSTFNAM	Test Facility Name	Example Tox Lab Name
10	123	ALLNRU	TS	1	1	TSTFLOC	Test Facility Location	10 Somewhere Street, Montgomery, AL 10000
11	123	ALLNRU	TS	1	1	TFCNTRY	Test Facility Country	USA
...	123	ALL NRU	TS	1	1	STDIR	Study Director	Dr. R. Smith
	123	ALLNRU	TS	1		GLPFL	GLP Flag	Y	123	MNvit	TS	1	ASTD	Assay Standard
	123	MNvit	TS	1	ASTDV	Assay Standard Version		123	MNvit	TS	1	SSTYP	Study Type	GENOTOXICITY IN VITRO	123	MNvit	TS	1	SSSTYP	Study Sub Type	In Vitro Micronucleus	123	MNvit	TS	1	SPECIES	Species	Homo Sapiens	123	MNvit	TS	1	??	Test System?	TK6 Lymphoblastoid Suspension Cells	123	NRU	TS	1	ASTD	Assay Standard	NIH Publication No. 07-4519
	123	NRU	TS	1		ASTDV	Assay Standard Version	2006-11
	123	NRU	TS	1		SSTYP	Study Type	GENOTOXICITY IN VITRO
	123	NRU	TS	1		SSSTYP	Study Sub Type	In Vitro Neutral Red Uptake
	123	NRU	TS	1		SPECIES	Species	Salmonella enterica
	123	NRU	TS	1		STRAIN	Strain/Substrain	Salmonella enterica enterica
	123	NRU	TS	1		??	Test System??	Normal Human Keratinocyte
	123	NRU	TS	1		REGIME	Smoking Regime	Traditional combustible
	123	NRU	TS	1		RUNPRT	run-port number?? (always same for whole assay?)	1-1
	123	NRU	TS	1		SMPLID	Sample ID	030001
	123	NRU	TS	1		SMKFRC	Smoke Fraction	A
	123NRU		TS	1		REPNUM	Replicate Number	1

...

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title	gt.xpt (similar to LB)

2022-05-25

Row	STUDYID	ASSAYID	DOMAIN	TXCD	GTSEQ	GTTESTCD	GTTEST	GTORRES	GTORRESU	GTSTRESC	GTSTRESN	GTSTRESU	GTDTC	GTNOMDY	GTELTM	GTTPTREF
1	123	NRU	GT	1-1-A	1	RELABS	Relative Absorbance Reading	100	ug/ml	100	100	ug/ml
2	123	NRU	GT	1-1-B	1	RELABS	Relative Absorbance Reading	107	ug/ml	100	100	ug/ml
3	123	NRU	GT	1-1-C	1	RELABS	Relative Absorbance Reading	98.6	ug/ml	100	100	ug/ml
54	123	NRU	GT	1-1-D	1	RELABS	Relative Absorbance Reading	94.9	ug/ml	100	100	ug/ml
6	123	NRU	GT	1-1-E	1	RELABS	Relative Absorbance Reading	111
7	123	NRU	GT	1-1-F	1	RELABS	Relative Absorbance Reading	96.9
8	123	NRU	GT	1-1-G	1	RELABS	Relative Absorbance Reading	105
9	123	NRU	GT	1-1-H	1	RELABS	Relative Absorbance Reading	95.2
10	123	NRU	GT	1-2-A	1	RELABS	Relative Absorbance Reading	83.0
11	123	NRU	GT	1-2-B	1	RELABS	Relative Absorbance Reading	77.7
...				...
80	123	NRU	GT	1-10-H	1	RELABS	Relative Absorbance Reading	0.791
...				...
160	123	NRU	GT	2-10-H	1	RELABS	Relative Absorbance Reading	0.780	1	123	MNvit	GT	A2	1	RICC	Relative Increase in Cell Count	134	15.7	%	15.7	15.7	%	2022-05-25	2	123	MNvit	GT	A2	2	RCC	Relative Cell Count	134	13.0	%	13.0	13.0	%	2022-05-25	3	123	MNvit	GT	A2	3	RPD	Relative Population Doubling	134	7.9	%	7.9	7.9	%	2022-05-25	4	123	MNvit	GT	A2	4	MNCELLS	Micronucleated Cells	3266	20	Cells	20	20	Cells	2022-05-25	5	123	MNvit	GT	A2	5	MNCELLS	Micronucleated Cells	2190	17	Cells	17	17	Cells	2022-05-25	6	123	MNvit	GT	A2	6	MNCELLS	Micronucleated Cells	2758	13	Cells	13	13	Cells	2022-05-25	7	123	MNvit	GT	A2	7	MNCELLS	Micronucleated Cells	2714	21	Cells	21	21	Cells	2022-05-25	8	123	MNvit	GT	A2	8	AVGREL	Average Relative MN Frequency	0.66	%	0.66	0.66	%	2022-05-25	9	123	MNvit	GT	A1	1	RICC	Relative Increase in Cell Count	154	0	%	0	0	%	2022-05-25	10	123	MNvit	GT	A1	2	RCC	Relative Cell Count	154	0	%	0	0	%	2022-05-25	11	123	MNvit	GT	A1	3	RPD	Relative Population Doubling	154	0	%	0	0	%	2022-05-25	12	123	MNvit	GT	A1	4	MNCELLS	Micronucleated Cells	3266	15	Cells	15	15	Cells	2022-05-25	13	123	MNvit	GT	A1	5	MNCELLS	Micronucleated Cells	2190	13	Cells	13	13	Cells	2022-05-25	14	123	MNvit	GT	A1	6	MNCELLS	Micronucleated Cells	2758	17	Cells	17	17	Cells	2022-05-25	15	123	MNvit	GT	A1	7	MNCELLS	Micronucleated Cells	2714	12	Cells	12	12	Cells	2022-05-25	16	123	MNvit	GT	A1	8	AVGREL	Average Relative MN Frequency	0.57	%	0.57	0.57	%

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