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title	tx.xpt (trial sets)

Treatment Duration will be controlled? During CT definition/revies will need to decide appropriate Treatment duration values; If not, what are best example values to show?

Row	STUDYID	ASSAYID	DOMAIN	SETCD	TXPARMCD	TXPARM	TXVAL
1	123	MNT	TX	A1	METACT	Metabolic Activation	+S9
2	123	MNT	TX	A1	TRTDUR	Treatment Duration	3 - 6
					TRTDURU		HShort Term
3	123	MNT	TX	A1	PRDCONC	Concentration of product	0
4	123	MNT	TX	A1	PRDCONCU	Concentration Unit	ug/ml
5	123	MNT	TX	A1	Product	Product Name
6	123	MNT	TX	A1		Smoking Regime
7	123	MNT	TX	A1		Smoke Fraction
	123	MNT	TX	A2	METACT	Metabolic Activation	+S9
	123	MNT	TX	A2	TRTDUR	Treatment Duration	Short Term
	123	MNT	TX	A2	PRDCONC	Concentration of product	1250
	123	MNT	TX	A2	PRDCONCU	Concentration Unit	ug/ml
	123	MNT	TX	A2	Product	Product Name
	123	MNT	TX	A2		Smoking Regime
	123	MNT	TX	A2		Smoke Fraction
	123	MNT	TX	B1	METACT	Metabolic Activation	-S9
	123	MNT	TX	B1	TRTDURT	Treatment Duration target	4 +/- 15m
					TRTDURTOLTRTDUR	Treatment Duration Tolerance	Short Term.25
??	123	MNT	TX	B1	TRTDURTRTDURU	Treatment Duration Long Term (or 2 parm codes, # and unit)Unit (this is for both TRTDURT, TRTDURTOL)	H
	123	MNT	TX	B1	PRDCONC	Concentration of product	0
	123	MNT	TX	B1	PRDCONCU	Concentration Unit	ug/ml
	123	MNT	TX	B1	Product	Product Name
	123	MNT	TX	B1		Smoking Regime
	123	MNT	TX	B1		Smoke Fraction
	123	MNT	TX	C1	METACT	Metabolic Activation	-S9
	123	MNT	TX	C1	TRTDUR	Treatment Duration	Long Term24
??	123	MNT	TX	C1	TRTDURTRTDURU	Treatment Duration Unit	HLong Term (or 2 parm codes, # and unit)
	123	MNT	TX	C1	PRDCONC	Concentration of product	0
	123	MNT	TX	C1	PRDCONCU	Concentration Unit	ug/ml
	123	MNT	TX	C1	Product	Product Name
	123	MNT	TX	C1		Smoking Regime
	123	MNT	TX	C1		Smoke Fraction

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title	concept maps?

Product, Smoking Regime (e.g. Traditional combustible, ENDS), Smoke Fraction, etc.

https://www.itis.gov/servlet/SingleRpt/SingleRpt?search_topic=TSN&search_value=969610#null

One study (Original sample of TK6 cells); (6 rows in GT)

Multiple products
Multiple Assays (Multiple types of assays)

Assay (MN Assay (MNT) (ran on 10 tobacco products)
3 assay/test conditions;
Treatment duration (2: ST, LT);
Presence of metabolic activation (2: presence, type)

Concentrations of product (6 of these: 0, x, y, z,..., +CNTL);
CytoTox % (3 different percentages from testing 1 portion of the original sample)
4 MN counts conducted (on 4 different portions of original sample?)

EID (5 of these, Count1 - Count4 and Cytotox): with many TX Parm codes??

Cytotox: RICC, RIC, RPD, #cells??

(also see Gentox notes on how to approach modeling, to apply that here?)

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