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TB-TAUG v2.0 Remodel in the IS domain
Model in IS, if you need to report changes in the actual level of IFN-y or number of IFN-y secreting cells, the stimulating and control agents used in the assay, and a "summary interpretation" result of positive, negative, or indeterminate, etc. In this case, you are testing and recording the explicit changes in the IFN-y release immune response, and this belong in the IS domain.
T-Cell ELISPOT:
| Dataset wrap |
|---|
| Dataset2 |
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| hi1style | yellow |
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| hi1 | column ISBDAGNT |
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| tableid | IS table 1 |
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| Row | NHOID | STUDYID | DOMAIN | USUBJID | SPDEVID | ISSEQ | ISGRPID | ISTESTCD | ISTEST | ISMSCBCE | ISTSTCND | ISCNDAGT | ISTSTDTL | ISORRES | ISORRESU | ISSTRESC | ISSTRESN | ISSTRESU | ISSPEC | ISMETHOD | ISDTC |
|---|
1 |
| ABC | IS | ABC-01-201 | ABC002 | 1 | 1 | CYKSCCL | Cytokine-secreting Cells | INTERFERON GAMMA | WITHOUT STIMULATING AGENT |
|
| 1 | SFC/10^6 PBMC | 1 | 1 | SFC/10^6 PBMC | PERIPHERAL BLOOD MONONUCLEAR CELLS | ELISPOT | 2013-08-26 | 2 | Mycobacterium tuberculosis | ABC | IS | ABC-01-201 | ABC002 | 2 | 1 | CYKSCCL | Cytokine-secreting Cells | INTERFERON GAMMA | WITH STIMULATING AGENT | CFP-10 |
| 13 | SFC/10^6 PBMC | 13 | 13 | SFC/10^6 PBMC | PERIPHERAL BLOOD MONONUCLEAR CELLS | ELISPOT | 2013-08-26 | | 3 | Mycobacterium tuberculosis | ABC | IS | ABC-01-201 | ABC002 | 3 | 1 | CYKSCCL | Cytokine-secreting Cells | INTERFERON GAMMA | WITH STIMULATING AGENT | ESAT-6 |
| 17 | SFC/10^6 PBMC | 17 | 17 | SFC/10^6 PBMC | PERIPHERAL BLOOD MONONUCLEAR CELLS | ELISPOT | 2013-08-26 | | 4 |
| ABC | IS | ABC-01-201 | ABC002 | 4 | 1 | CYKSCCL | Cytokine-secreting Cells | INTERFERON GAMMA | WITH STIMULATING AGENT | Mitogen |
| 30 | SFC/10^6 PBMC | 30 | 30 | SFC/10^6 PBMC | PERIPHERAL BLOOD MONONUCLEAR CELLS | ELISPOT | 2013-08-26 | | 5 | Mycobacterium tuberculosis | ABC | IS | ABC-01-201 | ABC002 | 5 | 1 | CYKSCCL | Cytokine-secreting Cells | INTERFERON GAMMA |
|
| INTERPRETATION | POSITIVE |
| POSITIVE |
|
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| ELISPOT | 2013-08-26 |
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TB-TAUG v1.0 Remodel in the MB domain
The Model in MB, the IGRA test is used to indicate whether a subject has ongoing or prior infection of a specific pathogen. In this case, you are doing a microbial detection test based on the interpretation of the IFN-y release immune response. You do NOT care or the lab does not provide you with actual results of the IFN-y related changes.
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