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 ODM v2.0 introduces nested ItemGroups. ItemGroupRef elements may be added to ItemGroupDef to create hierarchical data structures of arbitrary depth. Nested ItemGroupDefs can be used for enhanced re-usability of ItemGroups. They can  also represent semantic relationships between items, represent items that share common behaviors such as skip logic, or to represent items that are displayed or collected together.

The Coding child element allows to associate semantics within the group. For example a LOINC panel code in the case that the ItemGroup represents a laboratory panel.

The WorkflowRef child element allows to reference to a workflow definition (WorkflowDef) for navigation within the ItemGroup when it e.g. represents a form or questionnaire (or part of it) where there is a workflow between the items or groups of items.

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