Versions Compared

Old Version 17

changes.mady.by.user Jordan Li

Saved on

compared with

New Version 18

changes.mady.by.user Jordan Li

Saved on

Key

  • This line was added.
  • This line was removed.
  • Formatting was changed.

...

Info
titleQuestions and Thoughts

Imaging modality for the CV-imaging project:

Coronary angiography:

  1. Done on the chest area, the probe rotates around the chest of the subject, but there is no such a thing as "chest Coronary angiography", it is simply called Coronary angiography.
  2. Creates images of the entire coronary artery system

Thransthoracic Echocardiogram (TTE):

  1. Done on the chest and upper abdominal wall. The transducer is placed on various parts of the chest and upper belly to get different views of the heart. Again, there is no such a thing as chest TTE.
  2. Creates images of the heart.

Transesophageal Echocardiogram (TEE):

  1. Done from the inside of the Esophagus.
  2. Creates images of the heart.

Cine Angiography:

  1. Done on the chest, again the probe is placed on top of the chest.
  2. Creates images of the entire coronary artery system.

If we don't record the location for the procedures above, i,e, PRTRT = Coronary angiography, PRLOC = Chest, then why do chest and abdomen go into PRLOC for chest and abdominal CT scanscans?

A chest CT doesn't mean that a CT is done on the chest, it is a CT scan of the chest,  it creates images of the chest, more precisely the thoracic region. If PRTRT = CT Scan, PRLOC = Chest. The way I read this is that the CT scan is done on the chest, which doesn't make sense.

An abdominal CT doesn't mean a CT done on the abdomen, it is a CT scan of the abdomen, it creates images of the abdominal region.


Have I lose my god damn mind????

...

Dataset wrap
titlecv.xpt
NameTU


Rowcaps


Row 1:An aneurysm is present in the left renal artery.
Row 2:An aneurysm is present in the Infrarenal Aorta



Dataset2


TUGRPID

Row

STUDYID

DOMAIN

USUBJID

TUSEQTULNKID

TUTEST

TUORRES

TULOC

TULAT

TUMETHOD

VISITNUM

VISIT

TUDTC

31ABCTUABC-45631Aneurysm 1Aneurysm Identification

Target

Renal ArteryLeftMRI1BASELINE2020-04-27
52ABCTUABC-456522Aneurysm 2Aneurysm IdentificationTargetInfrarenal Aorta
MRI1BASELINE2020-04-27Aneurys



Case 2 - Subject has both TAA and AAA

...

Info
titleQuestions and Thoughts

The results for TU, TUORRES = target, non-target, or new target. This convention was designed for tumor assessment. Target and non-target have very specific definitions depending on the tumor under study. Generally for solid tumor, according to RECIST:

Measurable lesions - lesions that can be accurately measured in at least one dimension with longest diameter  20 mm using conventional techniques or 10 mm with spiral CT scan.

  • All measurable lesions up to a maximum of five lesions per organ and 10 lesions in total, representative of all involved organs should be identified as target lesions and recorded and measured at baseline.

Non-measurable lesions - all other lesions, including small lesions (longest diameter <20 mm with conventional techniques or <10 mm with spiral CT scan), i.e., bone lesions, leptomeningeal disease, ascites, pleural/pericardial effusion, inflammatory breast disease, lymphangitis cutis/pulmonis, cystic lesions, and also abdominal masses that are not confirmed and followed by imaging techniques.

  • All other lesions (or sites of disease) should be identified as non-target lesions and should also be recorded at baseline. Measurements of these lesions are not required, but the presence or absence of each should be noted throughout follow-up.

Since TU is also shared by Lesion Identification, to have a result as "target" is misleading and doesn't always apply to non-tumor settings. When you say there is a target aneurysm, what does that mean? Target for treatment and response evaluation? what is the criteria that makes it a target? Usually an aneurysm larger than 5cm requires surgery. Does that mean the ones that are smaller than 5 cm are considered "non-target"? and non-target for what? surgery not needed? The values for TU responses right now, doesn't make sense for non-tumor lesion identification process.


After all this, i struggle with what values should go into TULOC. When a CT scans the chest, it produces cross-sectional images of the thorax. You can view the images in three angles: axial view (you are looking at the picture of the thorax from the direction of head to toe), the coronal view (you are looking at the images of the thorax as if you are standing in front of the person),  sagittal view (you are looking at the picture of the thorax from the side). Hence TULOCs are populated with Thoracic Region and Abdominal Region. Especially in the axial view, as you move from cross-section images of the thorax to images of the abdomen, you are looking at sectioned images of the thoracic region to abdominal region.

Image Added