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Aortic Aneurysms in the aorta are classified based on their anatomical locations. Largely, they can be divided into two classes: thoracic aortic aneurysm (TAA), those that are in the thoracic aorta, and abdominal aortic aneurysm (AAA), those that are in the abdominal aorta.

Image RemovedAortic aneurysm finalImage Added

Thoracic aortic aneurysm (TAA) can further be divided into:

  1. Aortic root aneurysm
  2. Ascending aortic aneurysm
  3. Aortic arch aneurysm
  4. Descending aortic aneurysm
  5. Aneurysm that straddles multiple portions of the aorta (i.e. from aortic arch to descending aorta)

Image Modified

AAA can Abdominal aortic aneurysm (AAA) can be classified as:

  1. Suprarenal aortic aneurysm: above the kidneys
  2. Infrarenal aortic aneurysm: below the kidneys.
  3. Others: Pararenal, Jaxtarenal aortic aneurys.

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When a patient has abdominal aortic aneurysm of a substantial size, the patient may also have synchronous and metachronous thoracic aortic aneurysm. If causes and conditions are present to create an aneurysm in a large-medium size vessel in one place, you are more likely than those without those causes and conditions to have  (or develop) another aneurysm somewhere. The pressure from the medium to large aneurysm may also cause arterial dissection where the wall of the artery is tore, and a "false lumen" forms within the wall of the artery and blood can leak into it - leading to rupture.

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The figure below describes the general process flow from when a patient complains about the symptoms indicative of TAA and AAA to the diagnosis of TAA and AAA, followed by their subsequent evaluationevaluations. This is a summary of all the data collected.

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The concept map below transforms the general process figure above into CDISC-compliant format. Note the (TST) and (RES) prefixes are done intentional in the map below are used to show: test location and vs result location, respectively.

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The subject had a MRI performed on the upper body:.

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NamePR


Dataset2


Row

STUDYID

DOMAIN

USUBJID

PRSEQ

PRTRT

PRLOC

VISIT

 1  ABCPR  ABC-4561MRIUPPER BODYBASELINE



The evaluator then examined the MRI images of the thoracic cavity and abdominal cavity, and found the presence of a large AAA, but the absence of TAA.

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titlecv.xpt
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Row 1:I examined the MRI image of the thoracic cavity (test location) and didn't find the presence of an Aneurysmaneurysm.
Row 2:I examined the MRI image of the abdominal cavity (test location) and found an aneurysm in the left (Result LAT) renal artery (Result Loc).
Row 3:I examined the image of the abdominal cavity (test location) and found an aneurysm in the infrarenal aorta (Result Loc).
Row 4:I measured the diameter of the aneurysm in the left renal artery (test location).
Row 5:I measured the diameter of the aneurysm in the left renal artery the Infrarenal Aorta (test location).



Dataset2


Row

STUDYID

DOMAIN

USUBJID

CVSEQ

CVGRPID

CVTEST

CVORRES

CVORRESU

CVLOC

CVLAT

CVMETHOD

VISITNUM

VISIT

CVDTC


CVRESLOC
CVRESLAT
1ABCCVABC-4561
Aneurysm IndicatorN
Thoracic Cavity
CT SCAN1BASELINE2020-04-27


2

ABC

CVABC-45621Aneurysm IndicatorY
Abdominal Cavity
CT SCAN1BASELINE2020-04-27
Renal ArteryLeft
3ABCCVABC-45632Aneurysm IndicatorY
Abdominal Cavity
CT SCAN1BASELINE2020-04-27
Infrarenal Aorta
5ABCCVABC-45651Aneurysm Diameter2cmRenal ArteryLeftCT SCAN1BASELINE2020-04-27


6ABCCVABC-45662Aneurysm Diameter5cmInfrarenal Aorta
CT SCAN1BASELINE2020-04-27




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