...
- Where do you show that this challenge assay is done against TB antigens?
- CP domain has developed a new standard variable called Test Condition Agent/CNDAGT, which is used to map stimulating agents, like the values in ASSYAG, so this CP new variable can be added to LB?
- Lastly, this is a immunological test, should this be represented in LB?
- Use NHOID to show the name of the bug (in this case M. tuberculosis.) to which the INFg response is evoked? If we model this test in IS, what about its value IFNG test in LB. Or can we lab. We need to draw the line where if we are running a routine lab test looking for IFNg level it goes to LB vs IFNg response test toward a specific, known bug then it goes to IS? Addtionally we may want to use NHOID to show the bug in either LB or IS. If this test remains in LB, should NHOID be added to LB in order to show the name of the bug? I remember this being discussed by Jon/Bess when they worked on the TB TAUG.
...
| Dataset wrap |
|---|
| Dataset2 |
|---|
| hi1style | yellow |
|---|
| hi1 | column ISBDAGNT |
|---|
| tableid | IS table 1 |
|---|
|
Row | STUDYID | DOMAIN | USUBJID | ISSEQ | ISGRPID | NHOID | ISTESTCD | ISTEST | ISCNDAGT | ISTSTDTL | ISCAT | ISSCAT | ISORRES | ISORRESU | ISSTRESC | ISSTRESN | ISSTRESU | ISSPEC | ISMETHOD | VISITNUM | VISIT | ISDTC |
|---|
1 | ABC | IS | ABC-01-201 | 1 | 1 | Mycobacterium tuberculosis | IFNG | Interferon Gamma | Influenza A Virus
| Hemagglutination Inhibition Titer | VACCINE-RELATED IMMUNOGENICITY | HUMORAL IMMUNITY | 40 | titer | 40 | 40 | titer | SERUM | HEMAGGLUTINATION INHIBITION ASSAY | 1 | VISIT 1 | 2017-05-27 | Nil |
| 1.3 | IU/mL | 1.3 | 1.3 | IU/mL | PLASMA | ELISA |
|
|
| 2 | ABC | IS | TB1230-011 | 2 | 1 | Mycobacterium tuberculosis | IFNG | Interferon Gamma | ESAT-6, CFP-10, TB 7.7 |
| 6.2 | IU/mL | 6.2 | 6.2 | IU/mL | PLASMA | ELISA |
|
|
| | 3 | 2 | ABC | IS | TB1230-011 | 23 | 1 | Mycobacterium tuberculosis | IFNG | Interferon Gamma | Influenza B Virus
| Hemagglutination Inhibition Titer | VACCINE-RELATED IMMUNOGENICITY | HUMORAL IMMUNITY | 80 | titer | 80 | 80 | titer | SERUM | HEMAGGLUTINATION INHIBITION ASSAY | 1 | VISIT 1 | 2017-07-27 | 3 | ABC | | Mitogen |
| 0.9 | IU/mL | 0.9 | 0.9 | IU/mL | PLASMA | ELISA |
|
|
| | 4 | ABC | IS | TB1230-011 | 4 | 1 | Mycobacterium tuberculosis | IFNG | Interferon Gamma |
| Interpretation | Positive |
| Positive |
|
| PLASMA | ELISA |
|
|
|
|
|
Similarly if we were to model Jozef's request for https://loinc.org/95971-8/ - SARS CoV-2 stimulated gamma interferon [Presence] in Blood
| Dataset wrap |
|---|
| Dataset2 |
|---|
| hi1style | yellow |
|---|
| hi1 | column ISBDAGNT |
|---|
| tableid | IS table 1 |
|---|
|
Row | STUDYID | DOMAIN | USUBJID | ISSEQ | ISGRPID | NHOID | ISTESTCD | ISTEST | ISCNDAGT | ISTSTDTL | ISORRES | ISORRESU | ISSTRESC | ISSTRESN | ISSTRESU | ISSPEC | ISMETHOD | VISITNUM | VISIT | ISDTC |
|---|
1 | ABC | IS | ABC-01-201 | 1 | 1 | SARS-CoV-2 | IFNG | Interferon Gamma | Nil |
| 1.3 | IU/mL | 1.3 | 1.3 | IU/mL | PLASMA | ELISA |
|
|
| 2 | ABC | IS | TB1230-011 | 2 | 1 | SARS-CoV-2 | IFNG | Interferon Gamma | SARS-CoV-2 Antigen |
| 6.2 | IU/mL | 6.2 | 6.2 | IU/mL | PLASMA | ELISA |
|
|
| | 3 | ABC | IS | TB1230-011 | 3 | 1 | SARS-CoV-2 | IFNG | Interferon Gamma | Mitogen |
| 0.9 | IU/mL | 0.9 | 0.9 | IU/mL | PLASMA | ELISA |
|
|
| | 4 | ABC | IS | TB1230-011 | 4 | 1 | SARS-CoV-2 | IFNG | Interferon Gamma |
| Interpretation | Present |
| Present |
|
| PLASMA | ELISA IS |
|
|
|
|
|